著者

Zhao Ma Weiqin Li Jicui Yang Yijuan Qiao Xue Cao Han Ge Yue Wang Hongyan Liu Naijun Tang Xueli Yang Junhong Leng

出版者

The Japanese Society for Hygiene

雑誌

Environmental Health and Preventive Medicine (ISSN:1342078X)

巻号頁・発行日

vol.28, pp.4, 2023 (Released:2023-01-13)

参考文献数

56

被引用文献数

3

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Background: Congenital heart disease (CHD) is one of the most common congenital malformations in humans. Inconsistent results emerged in the existed studies on associations between air pollution and congenital heart disease. The purpose of this study was to evaluate the association of gestational exposure to air pollutants with congenital heart disease, and to explore the critical exposure windows for congenital heart disease.Methods: The nested case-control study collected birth records and the following health data in Tianjin Women and Children’s Health Center, China. All of the cases of congenital heart disease from 2013 to 2015 were selected matching five healthy controls for each case. Inverse distance weighting was used to estimate individual exposure based on daily air pollution data. Furthermore, the conditional logistic regression with distributed lag non-linear model was performed to identify the association between gestational exposure to air pollution and congenital heart disease.Results: A total of 8,748 mother-infant pairs were entered into the analysis, of which 1,458 infants suffered from congenital heart disease. For each 10 µg/m3 increase of gestational exposure to PM2.5, the ORs (95% confidence interval, 95%CI) ranged from 1.008 (1.001–1.016) to 1.013 (1.001–1.024) during the 1st–2nd gestation weeks. Similar weak but increased risks of congenital heart disease were associated with O3 exposure during the 1st week and SO2 exposure during 6th–7th weeks in the first trimester, while no significant findings for other air pollutants.Conclusions: This study highlighted that gestational exposure to PM2.5, O3, and SO2 had lag effects on congenital heart disease. Our results support potential benefits for pregnancy women to the mitigation of air pollution exposure in the early stage, especially when a critical exposure time window of air pollutants may precede heart development.

著者

Xi Ding Yang Zhao Chun-Ying Zhu Li-Ping Wu Yue Wang Zhao-Yi Peng Cuomu Deji Feng-Yi Zhao Bing-Yin Shi

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ20-0796, (Released:2021-04-21)

被引用文献数

19

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The association between subclinical hypothyroidism (SCH) and metabolic syndrome (MetS) has been widely discussed. This study aimed to conduct an update and comprehensive meta-analysis to reveal the risk of MetS and its components in SCH. PubMed, Embase and ISI Web of Knowledge were searched to identify relevant studies through February 20th, 2020. Review Manager 5.3 and Stata 14.0 were used to conduct the meta-analysis. Both fixed-effects and random-effects models were used. In total, 18 articles (19 studies) incorporating 79,727 participants were included. The pooled OR for MetS comparing subjects with SCH with euthyroid subjects was 1.28 (95% CI: 1.19 to 1.39, p = 0.04, I2 = 40%). Subgroup analysis results showed significant associations of SCH and MetS in the adult subgroup (OR = 1.28, 95% CI: 1.18–1.40), Asian population subgroup (OR = 1.30, 95% CI: 1.19–1.42) and cross-sectional study design subgroup (OR = 1.31, 95% CI: 1.16–1.47). Significant associations of SCH and MetS also existed in all MetS definition criteria subgroups except the Chinese Diabetes Society (CDS) subgroup. SCH was correlated with MetS and was not affected by the subgroup analysis stratified by the proportion of females in the total population, the TSH cutoff value in SCH diagnostic criteria, or the adjustment for confounding factors. SCH was identified to be associated with an increased risk of obesity, hypertension, high triglyceride (TG) levels and low high-density lipoprotein cholesterol (HDL-C) levels. In conclusion, SCH is significantly associated with an increased risk of MetS and four out of five components of MetS.

著者

Maziar NEKOVEE Yinan QI Yue WANG

出版者

一般社団法人 電子情報通信学会

雑誌

IEICE Transactions on Communications (ISSN:09168516)

巻号頁・発行日

vol.E100.B, no.8, pp.1181-1189, 2017-08-01 (Released:2017-08-01)

参考文献数

25

被引用文献数

10

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In order to support user data rates of Gbps and above in the fifth generation (5G) communication systems, millimeter wave (mm-wave) communication is proposed as one of the most important enabling technologies. In this paper, we consider the spectrum bands shared by 5G cellular base stations (BS) and some existing networks, such as WiGig and proposed a method for spectrally efficient coexistence of multiple interfering BSs through adaptive self-organized beam scheduling. These BSs might use multiple radio access technologies belonging to multiple operators and are deployed in the unlicensed bands, such as 60GHz. Different from the recently emerging coexistence scenarios in the unlicensed 5GHz band, where the proposed methods are based on omni-directional transmission, beamforming needs to be employed in mm-wave bands to combat the high path loss problem. The proposed method is concerned with this new scenario of communication in the unlicensed bands where (a) beam-forming is mandatory to combat severe path loss, (b) without optimal scheduling of beams mutual interference could be severe due to the possibility of beam-collisions, (c) unlike LTE which users time-frequency resource blocks, a new resource, i.e., the beam direction, is used as mandatory feature. We propose in this paper a novel multi-RAT coexistence mechanism where neighbouring 5G BSs, each serving their own associated users, schedule their beam configurations in a self-organized manner such that their own utility function, e.g. spectral efficiency, is maximized. The problem is formulated as a combinatorial optimization problem and it is shown via simulations that our proposed distributed algorithms yield a comparable spectral efficiency for the entire networks as that using an exhaustive search, which requires global coordination among coexisting RATs and also has a much higher algorithmic complexity.