- 著者
- Yusuke Ozawa Kosuke Oiwa Shunsuke Miyazaki Seiya Nishimura Yasushi Nanai Akio Nozawa
- 出版者
- The Institute of Electrical Engineers of Japan
- 雑誌
- 電気学会論文誌C(電子・情報・システム部門誌) (ISSN:03854221)
- 巻号頁・発行日
- vol.140, no.7, pp.769-774, 2020-07-01 (Released:2020-07-01)
- 参考文献数
- 19
- 被引用文献数
- 4
Long-term and continuous vital sign monitoring is essential for the early detection of hypertension. Blood pressure sensing based on non-contact biological measurement indices such as photoplethysmograms and skin temperature that can be obtained using visible light and infrared images has been attempted in previous studies. Near-infrared light has high transmissivity to living tissues and has been used for measuring arterial oxygen saturation. This study aims to improve the accuracy of non-contact blood pressure sensing using near-infrared light.
- 著者
- Yusuke OZAWA Shota TAKAHASHI Javier HERNANDO-AYUSO Stefano CAMPAGNOLA Toshinori IKENAGA Tomohiro YAMAGUCHI Bruno V. SARLI
- 出版者
- THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES
- 雑誌
- TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, AEROSPACE TECHNOLOGY JAPAN (ISSN:18840485)
- 巻号頁・発行日
- vol.17, no.4, pp.496-505, 2019 (Released:2019-07-04)
- 参考文献数
- 12
- 被引用文献数
- 1
OMOTENASHI is a 6U CubeSat that will be launched in 2019 by the Space Launch System (SLS) with the objective of landing on the Moon. The CubeSat is planned to perform two deterministic maneuvers. The first maneuver (DV1) by gas jet propulsion system transfers the probe from the nominal SLS trajectory to a lunar targeted trajectory. The second maneuver (DV2) is applied by the solid rocket motor before landing to counteract the vertical component of the S/C velocity. The high approach speed at the Moon, combined with large errors induced by the solid motor, requires the probe to approach the Moon with a shallow Flight Path Angle (FPA). If the angle is too steep, expected errors in the DV2 may cause the probe to crash. However, a shallow FPA increases the probability of a Moon-flyby or collision with the local topography. In this paper, we present a design method for Earth-Moon transfer trajectory robust to orbit determination (OD) and DV1 execution errors. First step consists of a grid search to determine the nominal DV1 vector with four candidates obtained. Subsequent error analysis suggests the need for a Trajectory Correction Maneuver (TCM). For the two scenarios of OD error provided by the navigation team, an error analysis was conducted including the TCM. Two realistic OD error scenarios were considered: 30 min or 3 hours of two-way Doppler and range measurement. Error analysis conducted considering TCM shows the need for 3 hours of OD to achieve nearly 100% of transfer success rate.
- 著者
- Nakaba MURATA Kazuma MURAKAMI Yusuke OZAWA Noriaki KINOSHITA Kazuhiro IRIE Takuji SHIRASAWA Takahiko SHIMIZU
- 出版者
- Japan Society for Bioscience, Biotechnology, and Agrochemistry
- 雑誌
- Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
- 巻号頁・発行日
- vol.74, no.11, pp.2299-2306, 2010-11-23 (Released:2010-11-23)
- 参考文献数
- 61
- 被引用文献数
- 63
Alzheimer’s disease (AD) is characterized by progressive cognitive impairment and the formation of senile plaques. Silymarin, an extract of milk thistle, has long been used as a medicinal herb for liver diseases. Here we report marked suppression of amyloid β-protein (Aβ) fibril formation and neurotoxicity in PC12 cells after silymarin treatment in vitro. In vivo studies had indicated a significant reduction in brain Aβ deposition and improvement in behavioral abnormalities in amyloid precursor protein (APP) transgenic mice that had been preventively treated with a powdered diet containing 0.1% silymarin for 6 months. The silymarin-treated APP mice also showed less anxiety than the vehicle-treated APP mice. These behavioral changes were associated with a decline in Aβ oligomer production induced by silymarin intake. These results suggest that silymarin is a promising agent for the prevention of AD.