- 著者
- Tomoe Yamada-Kato Isao Okunishi Yosuke Fukamatsu Hidenori Tsuboi Yusuke Yoshida
- 出版者
- Japanese Society for Food Science and Technology
- 雑誌
- Food Science and Technology Research (ISSN:13446606)
- 巻号頁・発行日
- vol.24, no.3, pp.567-572, 2018 (Released:2018-07-25)
- 参考文献数
- 30
- 被引用文献数
- 3 4
Wasabi is a member of the Brassicaceae family and produces various isothiocyanates (ITCs). Because 6-methylsulfinylhexyl ITC (6-MSITC) is stable among wasabi ITCs, it has potential as a functional compound. Hair loss can have psychological and social effects on an individual because of its impact on appearance. In this study, we investigated the stimulatory effects of 6-MSITC by culturing on human follicle dermal papilla cells (DPCs). Results showed that 6-MSITC significantly promoted DPC proliferation and upregulated vascular endothelial growth factor (VEGF) mRNA levels compared to control. Furthermore, 6-MSITC significantly upregulated adenosine A2b receptor (ADORA2b) mRNA levels. Previous studies have reported that VEGF was induced through ADORA1 and ADORA2 pathways. We suggest that 6-MSITC stimulates hair growth on DPCs related to the upregulation of ADORA2b mRNA level. Thus, 6-MSITC may be used as a functional compound.
- 著者
- Satoru YAJIMA Yuichi TAKASE Akira EJIRI Naoto TSUJII Hibiki YAMAZAKI Charles P. MOELLER Takahiro SHINYA Yuki TAKEI Yoshiyuki TAJIRI Yusuke YOSHIDA Akito SATO Akichika KITAYAMA Naoki MATSUMOTO
- 出版者
- The Japan Society of Plasma Science and Nuclear Fusion Research
- 雑誌
- Plasma and Fusion Research (ISSN:18806821)
- 巻号頁・発行日
- vol.13, pp.3402114, 2018-09-25 (Released:2018-10-17)
- 参考文献数
- 9
- 被引用文献数
- 3 9
In the TST-2 spherical tokamak device, we carried out a fully non-inductive current startup experiment by Landau damping of the Lower Hybrid Wave (LHW). Capacitively Coupled Combline Antennas (CCCAs) were used for wave injection. The antennas are located on the outboard side and the top side of the vacuum vessel, and by reversing the toroidal magnetic field, it is possible to simulate the case of wave injection from the bottom side. The highest plasma current of 26.7 kA was achieved by top injection with the reversed toroidal magnetic field. According to numerical calculation using ray tracing and Fokker-Planck codes (GENRAY/CQL3D), the downshift of the parallel wavenumber helped the tail of the electron velocity distribution extend to higher energy than the other cases. Additionally, in order to evaluate the directionality of the wavenumber spectrum which is also important for efficient current drive, a finite element solver (COMSOL) was used. In order to avoid deterioration of the wavenumber spectrum, one limiter of the outboard antenna should be moved away toroidally by 70 mm from the current position, and the preferred distance between the antenna and the cutoff density layer is about 2 cm.
- 著者
- Naoto TSUJII Yusuke YOSHIDA Yuichi TAKASE Akira EJIRI Osamu WATANABE Hibiki YAMAZAKI Yi PENG Kotaro IWASAKI Yuki AOI Yongtae KO Kyohei MATSUZAKI James H.P. RICE Yuki OSAWA
- 出版者
- The Japan Society of Plasma Science and Nuclear Fusion Research
- 雑誌
- Plasma and Fusion Research (ISSN:18806821)
- 巻号頁・発行日
- vol.15, pp.2402010, 2020-04-06 (Released:2020-05-08)
- 参考文献数
- 13
- 被引用文献数
- 2 4
Removal of the central solenoid is considered essential to realize a spherical tokamak fusion reactor, but non-inductive plasma start-up is a challenge. Start-up using lower-hybrid (LH) waves has been studied on the TST-2 spherical tokamak at the University of Tokyo. The equilibrium poloidal field is believed to be generated mostly by the wave driven fast electrons, which are highly non-thermal and have large orbit excursions from the flux surfaces due to low plasma current. Such an equilibrium can be qualitatively different from the Grad-Shafranov equilibrium routinely used for internal magnetic field reconstruction in a tokamak. In this work, the effect of fast electrons on the MHD equilibrium was investigated by considering the equilibrium solution of the hybrid-MHD model [Y. Todo and A. Bierwage, Plasma Fusion Res. 9, 3403068]. The fast electron distribution function was estimated using a LH current drive simulation based on ray-tracing and an orbit-averaged Fokker-Planck solver. The equilibrium solution of the hybrid-MHD model was successfully fitted to the magnetic and kinetic measurements. The resulting poloidal flux function was more skewed towards the outboard side when fast electrons were introduced, which was more consistent with the density profile measured by the Thomson scattering diagnostic.