- 著者
- Tomoe Yamada-Kato Isao Okunishi Yosuke Fukamatsu Hidenori Tsuboi Yusuke Yoshida
- 出版者
- Japanese Society for Food Science and Technology
- 雑誌
- Food Science and Technology Research (ISSN:13446606)
- 巻号頁・発行日
- vol.24, no.3, pp.567-572, 2018 (Released:2018-07-25)
- 参考文献数
- 30
- 被引用文献数
- 3 3
Wasabi is a member of the Brassicaceae family and produces various isothiocyanates (ITCs). Because 6-methylsulfinylhexyl ITC (6-MSITC) is stable among wasabi ITCs, it has potential as a functional compound. Hair loss can have psychological and social effects on an individual because of its impact on appearance. In this study, we investigated the stimulatory effects of 6-MSITC by culturing on human follicle dermal papilla cells (DPCs). Results showed that 6-MSITC significantly promoted DPC proliferation and upregulated vascular endothelial growth factor (VEGF) mRNA levels compared to control. Furthermore, 6-MSITC significantly upregulated adenosine A2b receptor (ADORA2b) mRNA levels. Previous studies have reported that VEGF was induced through ADORA1 and ADORA2 pathways. We suggest that 6-MSITC stimulates hair growth on DPCs related to the upregulation of ADORA2b mRNA level. Thus, 6-MSITC may be used as a functional compound.
- 著者
- Ryohei Nakano Hidemi Akimoto Fumio Fukuda Takashi Kawai Koichiro Ushijima Yosuke Fukamatsu Yasutaka Kubo Yuichiro Fujii Ken Hirano Kunihisa Morinaga Naoki Sakurai
- 出版者
- 一般社団法人 園芸学会
- 雑誌
- The Horticulture Journal (ISSN:21890102)
- 巻号頁・発行日
- pp.OKD-094, (Released:2017-10-12)
- 被引用文献数
- 15
Split-pit in peach fruit is a problematic disorder. Split-pit fruit cannot be detected based on external appearance, and contamination of fruit by split-pit reduces its reliability in the marketplace. Here, we demonstrate that split-pit fruit can be identified by a nondestructive acoustic vibration method and a unique approach based on the ratio of the third (f3) to the second (f2) resonant frequency. The response-resonant frequency spectra showed that the peaks of f2 frequencies in split-pit fruit were shifted to much lower values than those in normal fruit, whereas those of f3 frequencies showed only small shifts. The calculated f3/f2 ratios in most normal fruit were in the range of 1.35–1.4, whereas those in split-pit fruit were 1.45–2.0. Analysis of more than 300 fruit samples revealed that by setting the f3/f2 cut-off value at >1.45, 95% of split-pit fruit in the fruit samples were detected, whereas only 1.5% of normal fruit were missorted as split-pit fruit. A model for simulating the vibration properties of peach fruit was developed by using the finite element method. The simulated vibration patterns showed that f3/f2 values were increased by the insertion of split pit, indicating that, at least partially, the observed high f3/f2 values in split-pit fruit directly reflected split-pit occurrence. These results clearly demonstrate that the use of f3/f2 ratios obtained using an acoustic vibration method can effectively detect fruit with split-pit. The possibility of installing acoustic vibration devices in peach sorting lines and the application of portable devices to unpicked fruit on the tree are discussed.