著者
Tsutomu HOHDATSU Mika YAMADA Ritsuko TOMINAGA Kaori MAKINO Kouji KIDA Hiroyuki KOYAMA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.60, no.1, pp.49-55, 1998 (Released:2001-10-06)
参考文献数
34
被引用文献数
46 53

Infection of the type II feline infectious peritonitis virus (FIPV) strain 79-1146 to primary feline alveolar macrophages and human monocyte cell line U937 was enhanced by the sera of cats experimentally infected with the 79-1146 strain, but not those of cats infected with KU-2 or UCD-1 strain of type I FIPV. The experiments using sera of cats with feline infectious peritonitis (FIP) and of cats naturally infected with feline coronavirus (FCoV) revealed that infection of the FIPV 79-1146 strain to the U937 cells was enhanced only by the sera of cats infected with type II FIPV or feline enteric coronavirus. The samples positive for antibody-dependent enhancement (ADE) activity had high neutralizing antibody titers against the FIPV 79-1146 strain and the samples negative for ADE activity had low neutralizing antibody titers. These findings support the previous results where a monoclonal antibody with neutralizing activity had high ADE activity, suggesting that there was a close relationship between the neutralization and enhancement sites. And then it is also suggested that ADE of infection is likely to be induced by re-infection with the same serotype of virus in type II FIPV infection. Furthermore, U937 cells are considered useful and can be substituted for the feline macrophages for determining ADE of FIPV-infection.

言及状況

外部データベース (DOI)

Twitter (49 users, 69 posts, 73 favorites)

@JoanieOC @jonathanstea @Thinkingpowers @CaulfieldTim @RyanMarino @DrvanTilburg @doritmi @DrLindaMD @EdzardErnst @DrAliziAlias @DrAmalinaBakri @ScienceUpFirst @ArtKorenevsky I mean it killed all the animals in the trials of course it’s safe and effective! https://t.co/lKet11Gxii
@D16584667 @ukdutypaid2u @pjpeterman @Justinthejock @ColinDyckes Oh and here is the cat one https://t.co/zDgjRAONmd The only garbage is out of your mouth
@D16584667 @pjpeterman @Justinthejock @ColinDyckes Sorry forgot to add the cats one: https://t.co/zDgjRAONmd
@BlueCollarWrk @Justinthejock @ColinDyckes Sorry this is the ferret one, the end got cut off https://t.co/U0bEqgb2rL Cats also https://t.co/zDgjRAONmd
@sanjay_world Here are the same results in cats: https://t.co/2UZbc6Y57c And the same results in mice: https://t.co/5lyyhgiBAD https://t.co/65HCPrXjWC https://t.co/5eIcRq5GFu -
@RandomDevGuyC4F @Tangul_Bei @JordanSchachtel @FatEmperor @CDCgov Here are the same results in cats: https://t.co/iKvckxcNhM And the same results in mice: https://t.co/KT6M1vpTrd https://t.co/NUDh3Ft9HT https://t.co/6qEw0WdnuF
@AussieVal10 There is absolutely no need Mate. People keep forgetting that all the animals in the lab died after the Coronavirus Vaccine when they were exposed to "wild" Coronavirus. Cats - https://t.co/RWfpMfkEfF Mice - https://t.co/nxVoai0EdU Not to scare you though. Knowledge = Power
Antibody-Dependent Enhancement of Feline Infectious Peritonitis Virus Infection in Feline Alveolar Macrophages and Human Monocyte Cell Line U937 by Serum of Cats Experimentally or Naturally Infected with Feline Coronavirus Same results, the animals died… https://t.co/zLBb7wOnL1
@larrywright @jwgain01 @18posa11 @PoPoBeiBei @KarenBinz @DaveTDMD @charliekirk11 Here are the same results in cats: https://t.co/xgm25yiaDP And the same results in mice: https://t.co/6uMUc2KSj2 https://t.co/zW3vvjBWPW https://t.co/T0BVr0RV3v
@NoDirectAction Here are the studies:- Mouse:- https://t.co/km0ZQniGV5 Cats - https://t.co/RWfpMfkEfF It's all out there. Mainstream media will not cover it. Doesn't fit their narrative. #COVID19 #SARSCoV2 #CovidVaccines #covidvaccinedeaths
Antibody-Dependent Enhancement of Feline Infectious Peritonitis Virus Infection in Feline Alveolar Macrophages and Human Monocyte Cell Line U937 by Serum of Cats Experimentally or Naturally Infected with Feline Coronavirus
@AmeliaIris5 @firefly1379 Felines https://t.co/kgzFBoP9TN
@Yes99T @OdiSriUS These are the scientific studies that were done and if you read them, the results are horrifying. https://t.co/km0ZQniGV5 https://t.co/RWfpMfkEfF https://t.co/6aY2LFPOhk https://t.co/pOzPYAfhYo Keep reading and stay informed. Knowledge = Power
to application of a SARS-CoV vaccine in humans is indicated.” Here are the same results in cats: https://t.co/dyUsdftLYG And the same results in mice: https://t.co/Zt42avS5B4 https://t.co/kaT1JSMcha https://t.co/ngheuq4V3e
@IlchevLazar @Patriot06477197 @GeorgiBonchevBG @Parsifaler Here are the same results in cats: https://t.co/iKvckxuo9k And the same results in mice: https://t.co/KT6M1vHuiL https://t.co/NUDh3Fbyjj https://t.co/6qEw0WuYmd
@KyleBumpus @AlexBerenson Here are the same results in cats: https://t.co/9uI0BibLgI And the same results in mice: https://t.co/C1tHnDQWWZ https://t.co/LvJMAV7pHA https://t.co/zRgPTo6w3Q
aplicación de una vacuna contra el SARS-CoV en humanos". Aquí están los mismos resultados en gatos: https://t.co/bIJATFNhlN
Soooo this year could get very interesting
Antibody-Dependent Enhancement of Feline Infectious Peritonitis Virus Infection in Feline Alveolar Macrophages and Human Monocyte Cell Line U937 by Serum of Cats Experimentally or Naturally Infected with Feline Coronavirus https://t.co/RUoeeFNFte
"THIS SHOT" WHY WE DON'T - PREVIOUS LAB EXPERIMENTS - ALL animal trials in death of most or all of the animals. Study with ferrets from 2012: https://t.co/KGtTZTeMnQ Here are the same results in cats: https://t.co/fKW5631UX6 And the same results in mice: https://t.co/BqMRiQUzgN
ALL animal trials resulted in death of most or all of the animals. https://t.co/6OMfO6Zqty Here are the same results in cats: https://t.co/7V4vZPP6Le And the same results in mice: https://t.co/RGeUGV2Rq7 https://t.co/lHDtYb3YyS https://t.co/uRhX0udMrq -
@BOPDHB - animal trial for Sar co vax https://t.co/w5v72zG346 https://t.co/AktdE8i4Iq https://t.co/CEzDZeBg3U https://t.co/kyRPAMb25M https://t.co/SDW7sbPqwo -
Antibody-Dependent Enhancement of Feline Infectious Peritonitis Virus Infection in Feline Alveolar Macrophages and Human Monocyte Cell Line U937 by Serum of Cats Experimentally or Naturally Infected with Feline Coronavirus https://t.co/qWqxcSL3rM
@cathworkingmom @mfjlewis Here is the failed feline study: https://t.co/j3ASJc0nWw
@NikolovScience @truthismaster Tal conveniently left out the part about deadly antibody-dependent enhancement. Here they tried & failed to "vaccinate" for feline infectious peritonitis. If there has been a success story, I would like to read about it. I don't any. https://t.co/P06Db4O6E2
@ProfPaulYoung to elaborate a bit more: there's good evidence for ADE happening in FIPV (https://t.co/tSlGcpnPDn / https://t.co/Oz88HiSAP4 / https://t.co/6ga5TJa8zt / https://t.co/C6S6qIGTzF), & enough in-vitro data for *something* happening in this regard in clinical severe #SARSCoV2...

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