著者

Toshiki Fukui Kazuhiro Yamauchi Mie Maruyama Youichi Abe Sumie Yoshitaka Tadashi Yasuda

出版者

Japan Society of Ningen Dock

雑誌

Ningen Dock International (ISSN:21878072)

巻号頁・発行日

vol.2, no.2, pp.70-75, 2015 (Released:2018-12-10)

参考文献数

24

---

Objective: We previously reported the usefulness of brachial-ankle pulse wave velocity (baPWV) based on a cross-sectional analysis of data from Ningen Dock and general health screening. In our previous studies, we observed a strong relationship between the clustering of atherosclerosis risk factors and baPWV. In the present study, to evaluate this relationship further, we performed a longitudinal analysis over a 10-year period.Methods: Of the 22,377 individuals in whom baPWV was measured using form ABI/PWV at our facility, 626 males with measurements in both the first year and the 10th year were selected as subjects. Results: A significant positive correlation was observed between baPWV and the number of atherosclerosis risk factors in the first year of measurement, similar to our previous study. Over 10 years, the amount of change in all 626 males was about 100 cm/sec and the number of atherosclerosis risk factors increased from 1.3 to 1.6. The change in baPWV over 10 years tended to be smaller the greater the number of atherosclerosis risk factors. However, the values of baPWV in the 10th year were still higher when there were a greater number of risk factors. Conclusion: It is significant to measure baPWV continuously and pay attention to changes in it since it may be possible to suppress increases in baPWV by reducing the number of atherosclerosis risk factors. Furthermore, our findings suggest that early interventions in atherogenic risk control are required to reduce increases in the stiffness of large arteries.