著者

清水 昌 山田 秀明

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.39, no.6, pp.467-476, 1981-06-01 (Released:2009-11-13)

参考文献数

21

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Recent advances in the synthesis of useful organic compounds by enzymatic method are described. Various L-amino acids were synthesized by multifunctional pyridoxal enzymes; D-amino acids, especiall D-phenylglycine derivatives, by dihydropyrimidinase, purine arabinosides by nucleoside phosphorylases, insulin by proteases, steroid hormons by oxygenases, semisynthetic penicillins by penicillin acylase, and coenzyme A through biosynthetic pathway with pantothenic acid and L-cysteine under the coupling with ATP-generating system.The described enzymatic methods are simple and the most economical processes to date for the industrial production of these useful compounds.