Stefano Cattaneo DVM (@Albinovet)


an alternative combination therapy with metronidazole, clindamycin and doxycycline for #Babesia gibsoni (Asian genotype) in dogs in Hong Kong. The triple antibiotic protocol achieved an 87% success rate.
#antimicrobial susceptibility patterns of anaerobic bacteria identified from clinical specimens of diseased dogs&cats. The anaerobes included Bacteroides spp 33%, Peptostreptococcus 20%,Prevotella 14%,Propionibacterium 10%,Clostridium 9%& Fusobacterium 8%
transcorneal anterior chamber laser cyclophotocoagulation for the treatment of secondary #glaucoma with lens subluxation in a dog. Although this procedure is limited to the unlikely situation where the ciliary body is observable, it can reduce damage
pathological features of the atrioventricular conduction system in feline cases of 3rd-degree #atrioventricular_block. Histological examination of the AV conduction system revealed the marked reduction of conduction fibers due to fibrous replacement
proper fraction of inspired oxygen for reduction of O2-induced canine CSF hyperintensity on FLAIR using low-field #MRI. O2-induced CSF hyperintensity artifact is inevitable in FLAIR. Hypothesis supported that high FiO2 induces CSF hyperintensity artifact
distribution & epidemiological relatedness of methicillin-resistant #Staphylococcus aureus isolated from companion dogs, owners,& environments. A total of 65 S. aureus strains were isolated& 2% were MRSA displaying cefoxitin-resistance with mecA carriage
internal thoracic #veins: anatomy, plasticity and clinico-imaging relevance in small animal practice. Collateral internal thoracic veins pathways need to be distinguished from other vascular anomalies in dogs
association analysis of non-synonymous polymorphisms of interleukin-4 receptor-α and interleukin13 genes in canine #atopic dermatitis. Results from miniature dachshunds revealed a potential association between the presence of minor A allele rs24378020& CAD
treatment with rivaroxaban and monitoring of coagulation profiles in 2 dogs with venous #thromboembolism. Rivaroxaban was effective for the control of thromboembolism secondary to immune-mediated hemolytic anemia
pancreatic adenosquamous #carcinoma with invasion to the spleen in a cat. A pancreatic tumor infiltrated into the gastrosplenic ligament and spleen with regional lymph node and mesenteric metastases.
immunohistochemical analysis of beta-catenin, E-cadherin & p53 in canine gastrointestinal epithelial #tumors. The nuclear translocation of beta-catenin is important for the tumorigenesis of canine intestinal polypoid type adenocarcinomas
effects of #pentosan polysulfate on cell proliferation, cell cycle progression &cyclin-dependent kinases expression in canine articular chondrocytes. Its effect could be beneficial in the early stages of osteoarthritis treatment
argyrophilic nucleolar organizer regions #staining for cytology smears in dogs & cats. The argyrophilic nucleolar organizer regions are cellular proliferation markers, crucial for predicting the clinical course& aggressiveness of tumors.
the utility of dog leukocyte antigen typing for #transplantation medicine in dogs. The allogeneic transplantation results suggested that it is possible to prolong transplant engraftment by completely matching the DLA genotype between the donor &recipient
survey of #zoonotic pathogens in dogs and cats coordinating with public animal shelter in Niigata Prefecture, Japan. The prevalence of intestinal parasites in dogs &cats were 3.7% and 42.0%, & of diarrheagenic Escherichia coli were 19% & 15%, respectively.
biomarkers for #CKD in dogs: a comparison study. SDMA and cystatin C levels were significantly higher in dogs with CKD at various IRIS stages. Cystatin C level was the only biomarker that could indicate the earliest stage of CKD (IRIS stage I).
a feline case with multiple #fibrosarcoma and systemic fibromatosis associated with feline leukemia virus/feline sarcoma virus. Immunohistochemical analysis with anti-feline leukemia virus revealed cytoplasmic staining of proliferating spindle cells
a case of suspected subcorneal pustular #dermatosis in a French bulldog. Papule and pustule formations were observed throughout the body. Aseptic pustular dermatosis was diagnosed based on bacterial culture tests.
renal ultrasonographic strain elastography&SDMA in canine & feline #CKD. Strain elastography might be a promising imaging diagnostic tool for renal-elasticity evaluation, also correlating with renal functional impairment in canine and feline CKD
#cryptosporidium spp and cryptosporidiosis in Japan: a literature review and insights into the role played by animals in its transmission. Cryptosporidium infections are highly prevalent in animals in Japan
lobular diameters of autopsied dog livers give clues for an appropriate #liver #biopsy methodology. One would be able to obtain representative data of the entire liver by taking a sample from any single lobe except for the quadrate lobe.
the profile of urinary #lipid metabolites in cats. Focusing on oxidative pathway, 17 cyclooxygenase-metabolites and 5 metabolites produced by non-enzymatic pathway were detected.
an area ratio of thyroid gland to common carotid artery for evaluating the thyroid gland size. Thyroid gland area to common carotid artery (TG:CCA) was independent of both body weight, which may contribute to consistent measurement of thyroid size.
long-term outcome&progression of #osteoarthritis in uncomplicated cases of CCL rupture treated by #TPLO in dogs. Dogs would benefit from earlier surgical intervention through development of technology that enables early detection of ligament degeneration
effects of pupil size on canine visual #evoked_potential with pattern stimulation. The P100 implicit time at a small pattern size in the mydriasis group was significantly prolonged compared to the miosis group.
altered hepatic #cytochrome P450 expression in cats after chronic exposure to decabromodiphenyl ether
Acute monoblastic #leukemia in a FeLV-negative cat. Although the cat was treated with doxorubicin, cytosine arabinoside, and prednisolone, anemia did not improve without blood transfusion.
characterization of #Escherichia Albertii isolated from a dog. The isolate was resistant to penicillin,ampicillin,&erythromycin, as reported elsewhere. The current study suggests that dogs may act as a reservoir for this organism, transmitting it to humans
intramedullary spinal #nephroblastoma in a mixed breed dog
caudal vena cava #aneurysm in a cat with Eisenmenger Syndrome.
activation of butyrate-producing bacteria as well as bifidobacteria in the cat intestinal #microbiota by the administration of 1-kestose, the smallest component of fructooligosaccharide
paravertebral block using low-concentration lidocaine&dexmedetomidine for ovariohysterectomy in cats. Ataxia&urinary incontinence were not detected with any procedure, postoperatively. Paravertebral block resulted in a significant isoflurane-sparing effect
bladder&urethral transitional cell #carcinoma in a dog treated with total extirpation of the bladder, urethra,&vagina &with urinary diversion using a small intestinal conduit. Contrast-enhanced CT confirmed urinary discharge into the lumen.
malignant #ganglioneuroma in the bladder trigone treated with surgery in a dog
systemic #Inonotus sp. infection in a dog, presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged,&arrhythmia&tachycardia were auscultated. Clinical signs resolved for 325 days but the dog died suddenly
alterations in characteristics of canine articular #chondrocytes in non-passaged long-term monolayer culture.The chondrocytes phenotype could be partially redifferentiated through the spontaneous redifferentiation process in long-term cultures
the effect of insulin degludec, a long-acting insulin recently developed for use in humans , on glycemic control in #diabetic cats over a 12-month period. The mean insulin degludec dose was 0.75/kg/day. Long-term glycemic control was successfully achieved
clinicopathological features&outcomes of Miniature Dachshunds with #bone_marrow disorders. Immunosuppressive treatment-resistant animals in non-neoplastic bone marrow disorders showed distinct features, such as thrombocytosis&increased dysplastic features
decreased serum zinc concentration in dogs with lymphocytic-plasmacytic #enteritis LPE. Hypozincemia was observed in 51% of dogs with LPE. Serum zinc concentration is a useful biomarker for LPE severity and prognosis
repeated surgical treatment& long-term outcome of a cat with vertebral vascular #hamartoma. The resected mass was diagnosed as a vertebral vascular hamartoma. Clinical signs improved, but recurrence was diagnosed by MR& CT imaging at 7 months after surgery
cystine transporter expression is a marker to identify a subpopulation of canine adipose-derived #stemcells
Molecular detection of canine #respiratory pathogens between 2017 and 2018 in Japan.Bordetella bronchiseptica was most frequently detected, followed by canine herpesvirus 1, parainfluenza virus, pneumovirus, Mycoplasma cynos,& canine adenovirus type 2
canine mesenchymal stromal cell-conditioned medium promotes survival and neurite outgrowth of neural #stemcells.
hepatocellular necrosis with prominent regenerative reactions in a #zonisamide administrated dog. Serum biochemistry showed a markedly elevated ALP level. The dog died 6 days after the presentation
overexpression of human epidermal growth factor receptor 2 in canine primary lung #cancer. Immunohistochemical analysis revealed that of the primary lung cancer tissues, 69% were HER2 positive
use of oral paclitaxel for the treatment of bladder #tumors in dogs. Oral paclitaxel was well-tolerated. Clinical responses, including changes in mass size and improvement of clinical symptoms, were confirmed in some of the animals f
dog #steroidogenic factor-1, important in steroid hormone production: molecular cloning and analysis of epigenetic regulation. The authors identified the true full sequence of dog SF-1 cDNA. The gene is under the control of epigenetic regulation
preoperative planning for #TPLO based on proximal tibial width. This preoperative planning method allowed appropriate planning for TPLO with a clear index that was based on the size of the tibia rather than the breed or weight of the dog
use of #oclacitinib for a cat with pruritic dermatitis suffering chronic diarrhea during treatment with cyclosporine. Oclacitinib could be an effective treatment of pruritic dermatitis in cats,but clinicians need to pay close attention to immunosuppression
successful management with fipronil spray in a cat with #trombiculosis
dog-specific hemorrhagic changes induced by #liposomal formulations, in the liver &the gallbladder.
genome-wide DNA methylation analysis in canine gastrointestinal #lymphoma GIL. There was a large number of hypermethylated sites that are common in most of canine GIL. These abnormal DNA methylation could be involved in tumorigenesis
eosinophilic dermatitis and sebaceous #adenitis in the head and neck of a cat
effects of atenolol on left atrial and left ventricular function in healthy cats and in cats with #HCM. Multivariate logistic analysis revealed that atenolol was not associated with LA enlargement (LAE). Diastolic dysfunction may be associated with LAE;
localization of cerebral hypoperfusion in dogs with refractory and non-refractory #epilepsy using [99mTc] ethyl cysteinate dimer & single photon emission CT. The refractory epilepsy dogs showed more frequency area of hypoperfusion in temporal lobe
An aortic body #carcinoma with sarcomatoid morphology and chondroid metaplasia in a French Bulldog
establishment of rat anti-canine DEP domain containing 1B (DEPDC1B) #monoclonal antibodies. DEPDC1B was identified as an overexpressed gene in canine lymphoma. These antibodies can be important tools to investigate the role of DEPDC1B in canine tumors
Significant species differences in intestinal #phosphate absorption between dogs, rats, and monkeys. The intestinal phosphate absorption rate was the highest in dogs.
pharmacokinetics of single dose #sildenafil orally administered in canine models of chronic embolic #pulmonary_hypertension. The mean residence time&elimination half-life were slightly but significantly higher at a dose of 4 mg/kg than at a dose of 1 mg/kg
A Case of cat-to-human transmission of severe fever with #thrombocytopenia syndrome #virus
primary malignant peripheral #nerve_sheath_tumors arising from the spinal canal invading the abdominal cavity in a dog
comparison of the efficacy of cyclosporine&leflunomide in treating inflammatory colorectal #polyps in miniature dachshunds.While the response rates were higher in dogs treated with leflunomide,no significant differences were observed in the recurrence rate
aTeam technology for detecting early signs of #viral #cytopathic effect. ATP is the major energy currency of the cell. The ATeam technology is useful to determine the early signs of ATP-based CPE as early as 3h without morphology-based CPE by microscopy
detection of antibodies against #Toxoplasma gondii in cats using an immunochromatographic test (ICT) based on GRA7 antigen. There is no study yet documenting the potential for ICT serodiagnosis of T. gondii in cats. The t TgGRA7-ICT is a reliable test
cT of thoracic #lymph_nodes in dogs with no abnormalities in the dominated area. It was difficult to set a clinical index associated with size.Image findings that indicated abnormalities, such as circular shapes&non-uniform, may be routinely found in dogs
prevalence of 17 feline #behavioral problems& relevant factors of each behavior in Japan. 76% exhibited at least one behavioral problem. “Pica” & “Showing fear while on the examination table” were the most frequently reported behavioral problems
gas gangrene due to #Clostridium Novyi Infection in a dog . Gas gangrene and clostridial myositis are rare in dogs. Clostridium perfringens and Clostridium septicum have been identified as causative agents, but C. novyi was never reported
evaluation of the caudal vena cava diameter to abdominal aortic diameter ratio &the caudal vena cava respiratory collapsibility for predicting #fluid_responsiveness in dogs. The CVC/Ao measurement predicted stroke volume increase after a fluid bolus
effects of clamping umbilical cord on the neonatal viability of puppies delivered by #cesarean section. Keeping the umbilical cord intact for at least 3 min after the onset of breathing may contribute to increased vitality in puppies
a case of localized feline #demodicosis in the ear canals, refractory to a spot-on formulation of 10% imidacloprid&1% moxidectin, successfully treated with oral fluralaner (41 mg/kg).No mites were detected on direct microscopy 39 d after the administration
5 cases of #pectus_excavatum in cats surgically corrected by internal fixation with a small animal bone plate.Normalization of the thoracic morphology& disappearance of clinical symptoms were noted immediately after the operation&no recurrence was observed
infrared light photobiostimulation mediates periodicity in #Dirofilaria immitis microfilariae. Microfilariae exhibit nocturnal periodicity, with their numbers in peripheral blood peaking at night and decreasing during the day
hydrolyzed diets may stimulate food-reactive lymphocytes in dogs. The results demonstrate that hydrolyzed diets may contain proteins that stimulate helper T-lymphocytes, and may not be effective for treating all dogs with #food_hypersensitivity
prenatal diagnosis of foetal #hydrocephalus and suspected X-linked recessive inheritance of cleft lip in a Chihuahua
a case of feline skin dehiscence treated with the β-chitin #nanofiber ointment
long-term follow-up study after administration of a canine interferon-α preparation for feline #gingivitis. It was suggested that CaIFN-α have a reducing effect on gingivitis and halitosis for a certain period although may not on plaque or calculus
comparison of the effects of 4 prescription #diets on the fecal #microbiome in healthy dogs. The proportion of phylum Firmicutes was decreased with the weight-loss diet vs the anallergenic diet. Prescription diet influences the fecal microbiome in dogs
diffuse #leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund
analysis of passive tibio-femoral joint movement of dogs during flexion in cadaveric hind limbs without muscle. During the flexion of the stifle joint, approximately 20° of internal tibial rotation occurred around the longitudinal axis
pharyngeal contraction secondary to its collapse in dogs with #brachycephalic_airway_syndrome. Pharyngeal contraction during inspiration appears to contribute toward the worsening of clinical respiratory signs
a retrospective survey on canine #intracranial_tumors 2007-2017 in Japan. Among primary intracranial tumors, meningioma 51% was the most common. Regarding glial tumors, the incidence of oligodendroglial tumors 79% was higher than that of astrocytic tumors
cardiopulmonary changes induced by #retroperitoneal_nsufflation in dogs in sternal recumbency with the abdomen unsupported. Cardiopulmonary function was not compromised at any point. Thus, retroperitoneal CO2 insufflation up to 10 mmHg is well tolerated
microparticle-associated tissue factor activity (MP-TF) in dogs with #DIC. MP-TF activity positively correlated with plasma D-dimer concentration. Moreover, MP-TF activity was decreased by the time of recovery in some dogs with DIC
kestose supplementation (a fructooligosaccharide FOS) exerts bifidogenic effect within fecal #microbiota and increases fecal butyrate concentration in dogs
Correlation tween the width& number of QRS with the cardiac pathologic anatomy in canine cases of 3rd° #atrioventricular_block. The QRS duration indicated the locations of the severe conduction disturbances more favorably than the ventricular rate
a case of canine #hypoadrenocorticism needing blood transfusion for severe acute anemia due to gastrointestinal hemorrhage
phenobarbital-induced anticonvulsant #hypersensitivity syndrome in a cat. 8 days after initiation of phenobarbital treatment, the cat showed tachypnea and hyperthermia. After 10 days of cessation clinical signs were resolved.
physical signs of canine #cognitive_dysfunction CCD. Test results revealed that vision impairment, smell disturbance, tremor, swaying or falling and head ptosis were significantly associated with CCD
the effect of bamboo powder on #fecal_odor of dogs. The gas detector revealed that the mercaptan concentrations in the feces were reduced by feeding with bamboo powder for 7 d. Bamboo powder food additives provide a clear deodorization effect on dog feces
clinical findings& treatment of disseminated ‘ #Mycobacterium avium subspp hominissuis’ infection in a cat with diffuse parenchymal lung disease. Atonic seizures were observed during the treatment, it disappeared after isoniazid discontinuation
2 cases of canine functional parathyroid #adenoma. Parathyroid adenoma is a relatively rare disease in dogs. However, hypercalcemia caused by excessive secreted parathyroid hormone occurs as a paraneoplastic syndrome,&lowers the patient’s quality of life
human asymptomatic/smoldering Waldenstrom's #macroglobulinemia-like condition in a dog. Bone marrow cytology demonstrated an increased proportion of lymphoplasmacytic cell. A comprehensive screening did not confirm possible gammopathy-producing diseases
canine adrenocorticotropic hormone-producing sinusoidal #neuroendocrine_tumor associated with Cushing’s disease. CT & necropsy examination showed a mass across the frontal sinus and cerebral frontal lobe.
efficacy of #Juzen-taiho-to against vincristine-induced toxicity in dogs. This study suggested that Juzen-taiho-to may be applicable for gastrointestinal care in dogs receiving chemotherapy.
urinary excretion of liver-type fatty acid binding protein in #AKI model of cats. The results suggested that high L-FABP excretion is a pathophysiological response associated with antioxidant defense in proximal tubules with renal ischemia
melarsomine suppresses canine #osteosarcoma cell survival via inhibition of Hedgehog-GLI signaling
usefulness of #UP/C measurement (urinary protein/urinary creatinine ratio) for kidney disease in dogs and cats. Since there are weak correlations between blood creatinine& UP/C, UP/C is an independent index from blood creatinine.
molecular and serological survey of carnivore pathogens in free-roaming cats of rural communities in southern Chile. Overall observed occurrence was 7% for both #Anaplasma platys, & B. henselae, & 3.3% for both #Bartonella sp. and #Theileria equ
possible #antioxidative effects of long-term administration of Juzen-taiho-to in dogs at 450 mg/kg with food for 28 days. Juzen-taiho-to may have anti-oxidative effects in dogs by reducing oxidative stress&be useful for oxidative stress-related diseases
tissue factor procoagulant activity in the tumor cell lines& plasma of dogs with various #malignant_tumors. Hypercoagulability is a common paraneoplastic complication. Mammary tumor, hemangiosarcoma, & melanoma cell lines, expressed TF



A clinical case of presumed cerebellar medulloblastoma in a Japanese Black calf with increased neuron-specific enolase in cerebrospinal fluid.


A clinical case of presumed cerebellar medulloblastoma in a Japanese Black calf with increased neuron-specific enolase in cerebrospinal fluid.