著者
保田 静江 武藤 正 中岡 洋子 山下 朋子 岡村 好孝 柏木 哲夫 内藤 俊一
出版者
一般社団法人 日本医療薬学会
雑誌
病院薬学 (ISSN:03899098)
巻号頁・発行日
vol.8, no.3, pp.222-228, 1982-08-20 (Released:2011-08-11)
参考文献数
4

Brompton mixture was used for reducing the pain in cancer patients at the terminal stage. The mixture was effective in treatment and caused no adverse reactions, such as cloudiness of consciousness, personality deviation, and psychological dependency and tolerance. Some patients were able to take the mixture orally until the day just before death. The effectiveness of the Brompton mixture was investigated on 34 patients. It was considered that the increase in dose to reduce a pain might be due to the increase of pain associated with exacerbation of cancer and/ or malabsorption of morphine rather than drug tolerance to morphine. Morphine concentration in plasma of a patient with pain well-controlled by the mixture was about 0.4μg/ml. Adverse reactions of the Brompton mixture were decreased in parallel with the use of prochlorperazine and other drugs.
著者
中岡 洋
出版者
成蹊大学
雑誌
成蹊大学一般研究報告 (ISSN:03888835)
巻号頁・発行日
no.9, pp.41-66, 1973-03
著者
中岡 洋
出版者
早稲田大学英文学会
雑誌
英文学 (ISSN:04246861)
巻号頁・発行日
no.33, pp.70-80, 1968-12
著者
中岡 洋
出版者
成蹊大学
雑誌
成蹊大学一般研究報告 (ISSN:03888835)
巻号頁・発行日
no.21, pp.p21-221, 1984-09