2 0 0 0 OA エンドトキシンショックにおける血管内凝固症候群と臓器不全の臨床的検討
- 著者
- 金子 弘真 高塚 純 柴 忠明 竹内 節夫 斉藤 徹 五十嵐 紀子 浅田 敏雄
- 出版者
- The Japanese Society on Thrombosis and Hemostasis
- 雑誌
- 血液と脈管 (ISSN:03869717)
- 巻号頁・発行日
- vol.15, no.3, pp.274-276, 1984-06-01 (Released:2010-08-05)
- 参考文献数
- 7
(Multiple organ failure) MOF or (Disseminated intravascular coagulation) DIC often becomes a fatal complication for the patients suffering from endotoxin shock. And it is also pointed out that MOF and DIC share many common or simiar clinical features. To clarify the relationship between these two, we surveyed the changes in haematological indices of organ failure patient.DIC was complicated in 10 of 14 patients with endotoxin shock and 9 of these were victimized. In the latter 9 cases, failure of more than three organs occured concomitantly. DIC observed in patients with organ failure is as follows: 10 in 13 cases of lung failure, 3 in 5 cases of heart failure, 10 in 12 cases of renal failure, 3 in 5 cases of liver failure and 3 in 4 cases of gastro-intestinal bleeding. Both organ failure and DIC usually began at the lung in endotoxin shock patients. From the viewpoint of haematology, hypercoagulable tendency preceded the lung failure. For example, decrease in antithrombin III and plasminogen level was observed prior to that in platelet.In endotoxin shock patients, MOF and DIC have close relationship, which suggests that hypercoagulable state induced by endotoxin triggers an organ failure and results in MOF through chain reactions.
1 0 0 0 IR 2型バゾプレッシンレセプターのラット脳内局在について
- 著者
- 加藤 陽一郎 五十嵐 紀子 平澤 明 辻本 豪三 小林 槇雄
- 出版者
- 東京女子医科大学学会
- 雑誌
- 東京女子医科大学雑誌 (ISSN:00409022)
- 巻号頁・発行日
- vol.65, no.6, pp.485-485, 1995-06-25
第6回東京女子医科大学遺伝医学研究会 1994年11月26日(土) 中央校舎4階講義室(400号室)