1 0 0 0 OA 耳鳴に対する牛車腎気丸の効果
- 著者
- 荻野 敏 原田 保 坂口 喜清 柳 英博 丹生 真理子 仙波 治 入船 盛弘 田矢 直三 野入 輝久 坂本 邦彦 荻野 仁
- 出版者
- 耳鼻咽喉科臨床学会
- 雑誌
- 耳鼻咽喉科臨床 (ISSN:00326313)
- 巻号頁・発行日
- vol.91, no.2, pp.199-204, 1998-02-01 (Released:2011-11-04)
- 参考文献数
- 7
- 被引用文献数
- 4 6
Treatment of tinnitus is often difficult. In this study, we evaluated the effectiveness of a Chinese medicine, Gosha-jinki-gan, for the treatment of tinnitus. Forty-two cases, comprising a total of 58 ears, received Gosha-jinki-gan at a dose of 7.5 g a day for at least 4 weeks. Efficacy was evaluated on the basis of changes in symptoms before and after treatment. In total, twenty-seven out of 58 ears (46.6%) improved. The final improvement rate was higher in the group with hearing loss than in the group without hearing loss. It was also greater in the group without pre-treatment than in the group with pre-treatment, however, co-treatment did not influence the improvement rate. No adverse reactions were evident. From these results, it was thought that Gosha-jinki-gan might be useful in the treatment of tinnitus.
- 著者
- 荻野 敏 入船 盛弘 後藤 啓恵 仙波 治 野入 輝久
- 出版者
- 耳鼻咽喉科臨床学会
- 雑誌
- 耳鼻咽喉科臨床 (ISSN:00326313)
- 巻号頁・発行日
- vol.92, no.3, pp.309-324, 1999-03-01
- 参考文献数
- 13
- 被引用文献数
- 4
The clinical efficacy and safety of 200 μg/day (100μg b. i. d) of mometasone furoate nasal spray (MFNS) administered for 2 weeks was evaluated by comparison with a low dose of MFNS of 50μg/day (50μg o. d.) using the envelope-method in a total of 65 patients with Japanese cedar<br>pollenosis.<br>The pollen counts for Japanese cedar in 1995 were extremely high in the Kansai district. About 5, 000 counts/cmz was confirmed in and around Osaka.<br>In the analysis of final overall improvement, marked or moderate improvement was observed in 76.2% (16/21) and 20.8% (5/24) of patients receiving MFNS 200μg/day and 50μg/day, respectively. The difference in efficacy between the two dosage groups was confirmed independently of timing of the initiation of administration. In the analysis of overall safety, high safety was observed with both treatments. The above results suggest that 200μg/day of MFNS can be considered the recommended dose for the treatment of Japanese cedar pollenosis.