1 0 0 0 神経細胞に対する力学負荷実験および損傷評価手法の開発
- 著者
- 仲町 英治 三木 一生 古川 一憲 武川 雄一 土井 哲平
- 出版者
- 一般社団法人日本機械学会
- 雑誌
- 日本機械学会論文集. A編 = Transactions of the Japan Society of Mechanical Engineers. A (ISSN:03875008)
- 巻号頁・発行日
- vol.71, no.701, pp.73-79, 2005-01-25
- 参考文献数
- 9
- 被引用文献数
- 2
In this paper, a new head injury criterion evaluated by the hydrostatic stress occurred in the head crash phenomenon. In order to obtain the threshold value for brain's organ and tissue, <I>in vitro</I> impact experiments to cultured nerve cells were performed. PC-12 cultured nerve cell was employed to imitate the human's nerve cell. In the experiments, various pressure waves were generated by introducing different heights of dropping weight for impacting. Relationships between peak values of impact compressive and expansive pressure waves and detachment rates and injury rates evaluated by the cell membranes damage were obtained.
