著者

堀井 聰 野口 友昭 松井 勇作 渡辺 順明 後藤 実

出版者

日本生薬学会

雑誌

生薬学雑誌 (ISSN:00374377)

巻号頁・発行日

vol.14, no.2, pp.91-94, 1960

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In the course of studies on antibiotic components of plants, an antibacterial pigment was isolated from the outer bark of the root of "Tsuru-ume-modoki" (Celastrus orbiculatus THUNB.) after finding that a 50 % methanolic extract of the root of the plant had antibacterial activity. The pigment was identified as celastrol, which had been isolated from the root bark of Celastrus scandens by O. Gisvold. Further the pigment was found to have not only antibacterial but also antifungal and antitumor activities. Investgation was also carried out on some plants of the genera Tripterygium and Euonymus.