著者

太田 美穂 松原 良太 川野 真太郎 大部 一成 緒方 謙一 中村 誠司

出版者

日本口腔内科学会

雑誌

日本口腔内科学会雑誌 (ISSN:21866147)

巻号頁・発行日

vol.20, no.2, pp.47-51, 2014 (Released:2015-09-06)

参考文献数

16

被引用文献数

1 2

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抜歯後出血は局所的要因に起因することが多いが,出血性素因から生じる場合もある。本報告は,80歳代女性の抜歯後出血を契機に明らかとなった慢性播種性血管内凝固症候群(DIC)の1例である。血液検査でDICに起因する止血凝固異常と診断され,トロンボモジュリン製剤投与にてDICは改善したが,その原因となる基礎疾患は認められなかった。治療終了後は経過観察を行っているが,DICの再燃なく経過良好である。

著者

大関 悟 大部 一成 田代 英雄

出版者

社団法人 日本口腔外科学会

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.33, no.3, pp.627-634, 1987-03-20 (Released:2011-07-25)

参考文献数

16

被引用文献数

1 1

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Thermotherapy by 2450 MHz microwaves was performed on oral cancer patients and its effectiveness was analyzed and evaluated.Subjects were 7 primary oral cancer patients (4 lower gum cancer, 2 buccal mucosa and 1 oral floor) and 5 recurrent cancer patients (3 with cheek lesion and 2 with neck lesion). Heat was generated by a microwave apparatus of 2450 MHz.Seven cases which received intraoral thermotherapy on primary lesions were treated in combination with radiation and bleomycin. Thermotherapy was performed twice a week, up to 5-8 times in total, applyied immediately after the radiation therapy. Intraoral applicator was a flexible leakage-type coaxial applicator 2-4 mm in diameter and 40-90 mm in length. It was modified depending on each tumor size and shape. Tumor surface was heated to 42-45°C for 30-50 minutes and the heat distribution pattern of each modified applicator was checked using Phantom Model. Of the seven lesions, 6 (85.7%) showed complete regression (CR) and one showed partial regression (PR). Histological examination was made on five cases which received surgical tumor resection. Among them, one was grade III and the rest were grade IIb by Simosato's criteria. Tumor necrosis and mucosal reaction were seen at the heated site from the early stage of treatment and the thermotherapy was obviously effective.Five recurrent cancer patients received extraoral thermotherapy without radiotherapy on the cheek or neck lesions using the non-contact type applicator. Tumor necrosis was limited to the surface area and the regression effect was minimum which might be due to the lack of combination therapy of radiation.Thermotherapy seemed effective for the oral cancer when used in combination with radiation. However, more clinical experience is needed to evaluate the usefullness of this treatment.