著者
川田 賢介 河原 正和 秋森 俊行 山口 朋子 岡本 喜之 石川 好美
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.54, no.7, pp.423-426, 2008-07-20 (Released:2011-04-22)
参考文献数
23
被引用文献数
1 1

Oral mucosal lesions associated with foreign body injuries can have various origins, but traumatic lesions of the oral mucosa caused by other organisms are rare. Such cases thus require special knowledge for diagnosis. We report a case of oral stings from spermatophores of Todarodes pacificus, the Pacific squid. The patient was a 31-year-old woman who cooked the internal organs of a raw T. pacificus for lunch. She experienced a sharp pain on the tongue and buccal mucosa when eating the organs. On checking the oral cavity, she identified multiple white objects with a worm-like appearance sticking into the tongue and oral mucosa. Attempts to remove these objects herself were unsuccessful. She then visited the emergency department of our hospital. We examined the oral cavity and found multiple white objects appearing to be parasitic worms sticking into the tongue and oral mucosa. Attempts to remove the objects with forceps were unsuccessful because of tight attachment to the mucosa. Removal was thus achieved by making slight incisions under local anesthesia. The specimens showed a white spinate shape and were about 4mm long. Endoscopic examination of the upper digestive tract after treatment of the oral cavity revealed no additional foreign bodies. The final pathological diagnosis was spermatophores of T. pacificus.
著者
下村 忠弘 山本 一彦 栗原 都 柳生 貴裕 高野 梨沙 桐田 忠昭
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.58, no.10, pp.600-603, 2012-10-20 (Released:2014-11-20)
参考文献数
18

A case of sting wounds of the oral mucosa caused by spermatophores of a raw squid is reported. The patient was a 61-year-old woman. She noticed pain of the oral mucosa immediately after eating part of a raw squid. Several milky white, club-shaped foreign bodies measuring 3 to 5 mm were stuck in the tongue, buccal mucosa, and floor of the mouth. These were not mobile and were hard to remove. The clinical diagnosis was sting wounds of the oral mucosa caused by spermatophores of a squid. These foreign bodies were excised together with the surrounding tissue under local anesthesia. Wound healing was uneventful. Histologically, the foreign bodies contained numerous spermatozoa and were identified as spermatothecae, which were ejected from the spermatophores of a raw squid.
著者
木下 靖朗 冨田 陽二 早瀬 智広 中野 稔也
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.39, no.9, pp.993-995, 1993-09-20 (Released:2011-07-25)
参考文献数
13

This report presents rate two cases of foreign bodies (sperm-bags of squid) in the oral cavity, which were found in a 38-year-old male and 49-year-old female.Several small thorn-shaped foreign bodies stuck in the oral mucosa were observed and removed successfully.
著者
渋谷 恭之
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.56, no.6, pp.346-351, 2010-06-20 (Released:2013-10-19)
参考文献数
14

The current foundation of preventing nosocomial infection in dental settings are “Guidelines for infection control in dental health-care settings” announced in 2003 by Centers for Disease Control and Prevention (CDC). These guidelines employ a concept of standard precaution in clinical dentistry, and had a great influence on “Guideline for infection control in dental prosthetics” established in 2007 by Japan Prosthodontic Society and “Guideline for infection control in dentistry” announced by the dental division of the infection control conference of the national university hospitals in 2008. On the other hand, there have been many reports about oral care, for instance, ‘1) oral care prevents aspiration-related pneumonia', ‘2) oral care decreases the onset rate of the influenza to a one-tenth, (oral care decreases significantly neuraminidase and protease which bacteria produce) ', ‘3) oral care reduces a side effect in the oral cavity by the chemoradiotherapy', ‘4) oral care prevents ventilator-associated pneumonia in ICU', ‘5) oral care is useful for symptom relief in terminal illness', and an importance of oral care has been widely noticed in late years.
著者
前田 初彦
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.56, no.8, pp.464-470, 2010-08-20 (Released:2013-10-31)
参考文献数
36

In humans over 120 human papillomavirus (HPV) types have been completely described. HPVs have also been classified as low and high risk HPV types based on the clinical behavior of the HPV infected tissues. HPV proteins, especially the oncoproteins E6 and E7 of the oncogenic HPVs, interact with different degrees of affinity, with host cell proteins to disturb the normal epithelial differentiation and apoptosis by stimulating cellular proliferation, DNA synthesis and inhibition of cell cycle regulators. The best characterized interactions so far are the interactions between E7 and pRb and E6 and p53. Continued and aberrant expression of the E6 and E7 genes of the high risk HPVs will lead to genomic instability which finally after accumulation of mutational events can result in malignant transformation. Persistent infection with high risk HPV increase the risk of squamous cell carcinoma, while the low risk HPV may be associated with benign lesions. Also, HPV infections can be detected in the oral cavity and HPVs have been described as being associated with malignant lesions, such as oral squamous cell carcinoma and with benign lesions such as leukoplakia and oral papilloma. It is suggested that oral mucosa might serve as a reservoir of HPVs. Now, an inoculation of vaccine preventing HPV infection is performed, and the result begins to appear for the prevention of the cervical cancer. In addition, an improvement in the state of oral hygiene decreases the rate of HPV infection, and indicated that oral care may be an effective way to prevent HPV infections. The present conditions and the future prospects of the prevention and the treatment of HPV infections in the oral region are reported.
著者
豊福 明
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.55, no.4, pp.163-168, 2009-04-20 (Released:2012-08-28)
参考文献数
25
被引用文献数
1 1

In dry mouth clinic, there are many patients who complained of subjective feelings of dry mouth despite their normal salivation. This dry mouth frequently comorbid with glossodynia or oral dysaesthesia. So far, these complaints have been thought to be ‘psychogenic’. Namely, psychosocial factors and/or individual factors have long been considered as main cause. Even if oral surgeons referred patients to psychiatry clinic, a majority of them wished to avoid consultation, or, would sometimes complain that the dry mouth got worse after medication. Therefore, it is very important and difficult problems for clinical oral surgeons to see how look at these patients and to learn how cope with them.From my own years of experience in psychosomatic studies, I think ‘distorted cognition ’ is central to these pathogenesis. These distorted cognition cause dissociations between subjective and objective findings. Moreover, I have propose a hypothesis that neurochemical dysfunction of some sort of neurotransmitter systems and distortions of information-processing in cerebral association area related to thought and memory underlie the distorted cognition.Patients with subjective dry mouth never tell a lie about their symptoms, but they have just ‘ neural network error’ in their brain. We should take up to problems of oral discomfort at the root of their complaint.If we suspect their complaints as the cause of psychogenic, it might be often unsuccessful in treatment. First of all, to listen carefully to complaints from them is very important, and then we have to do differential diagnosis. If patients are diagnosed the symptom form with distorted cognition, medication using SSRI or SNRI is necessary for reconstruction of impaired neuronal network. Of course oral surgeons have to receive advanced education and training to use psychotropic drugs. At the same time, it is needed for sensitive response to patients and family members.The distorted cognition with these patients are associated with dysfunction of neurotransmitter systems and information-processing in peripheral to higher central nervous system. Strange complaints and persistent therapeutic demand are representatives of the distorted cognition. If we regard queer complaints as neural network errors, we can see the psychogenic complaints as distorted cognition.At present, this hypothesis cannot be shown objectively, but it might be possible that some new approaches such as brain imaging make mechanisms of the distorted cognition more clear. It is very important to collect evidence-based diagnosis, therapies and pathophysiological mechanism for dry mouth as an oral psychosomatic disorder.
著者
河野 峰 柴田 敏之 永易 裕樹 北所 弘行 中田 大地 有末 眞
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.44, no.1, pp.16-21, 1998-01-20 (Released:2011-07-25)
参考文献数
13

We studied whether epidermal growth factor (EGF) enhances the motility of human oral squamous cell carcinoma (SCC) cells in an autocrine manner. The motility of five SCC cell lines (SAS, Ca 9-22, HSC-2, -3, -4) was examined with the use of a phagokinetic track assay. The motility of SAS cells and HSC-2 cells was significantly increased without EGF stimulation as compared with the three other cell lines. Amounts of EGF in the culture supernatants of the five cell lines after 48h of culture were examined with the immunoblotting method. EGF was detected in the supernatants of SAS cells and HSC-2 cells (SAS, 8.65±0.45; HSC-2, 2.60±1.13ng/ml). SAS cells, showing the highest levels of motility and EGF production, was used for further study. When SAS cells were treated with anti-EGF antibody, anti-EGF receptor antibody, and erbstatin analog, the motility of SAS cells was significantly inhibited. Furthermore, the culture supernatant of SAS cells enhanced the motility of HSC-3 cells in a concentration-dependent fashion. These results suggest that EGF may stimulate the motility of human oral SCC cells in an autocrine manner.
著者
林 良夫
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.57, no.5, pp.234-237, 2011-05-20 (Released:2014-05-22)
参考文献数
8

Primary Sjören’s syndrome (SS) is an autoimmune disorder characterized by lymphocytic infiltrates and destruction of the salivary and lacrimal glands, leading to clinical symptoms of dryness of the mouth and eyes. Autoreactive T cells bearing CD4 molecule may recognize unknown self antigen, triggering autoimmunity in the salivary and lacrimal glands. Recent evidences suggest that the apoptotic pathway plays a central role in tolerazing T cells to tissue-specific self antigen including 120KD α-fodrin, and may drive the autoimmune phenomenon. Cleavage of certain autoantigens during apoptosis may reveal immunocryptic epitopes that could potentially induce autoimmune response. It is now evident that the interaction of Fas with FasL regulates a large number of pathophysiological process of apoptosis including autoimmune diseases. Our data imply that tissue-specific apoptosis and caspase-mediated α-fodrin proteolysis are involved in the progression of autoimmune lesions in SS. We found that retinoblastoma-associated protein RbAp48 overexpression induces apoptosis in the salivary glands caused by estrogen deficiency. The studies reviewed the pathology and molecular mechanisms on the development of SS.
著者
鈴木 大貴 濱田 裕嗣 高橋 美穂 唐木田 一成 坂本 春生
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.64, no.2, pp.88-91, 2018-02-20 (Released:2018-04-20)
参考文献数
10

Sweet’s Syndrome is a disease characterized by multiple nodules or edematous erythema elevatum of the face, neck, and skin, accompanied by acute fever and peripheral leukocytosis. This disease is considered one of the paraneoplastic syndromes of blood tumors. A 50-year-old Japanese man was referred to our department because of oral mucosa hyperplasia. The patient who had the various condition and we performed various examination, but needed long time for definitive diagnosis. In this article, we report a case of oral mucosa hyperplasia caused by Sweet’s Syndrome that was difficult to diagnose.
著者
藤野 博
出版者
社団法人 日本口腔外科学会
雑誌
口腔外科学会雑誌 (ISSN:04541693)
巻号頁・発行日
vol.12, no.1, pp.1-20, 1966-04-01 (Released:2011-07-25)
参考文献数
52
被引用文献数
1
著者
覚道 健治
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.61, no.9, pp.440-448, 2015-09-20 (Released:2015-12-09)
参考文献数
17

Regarding the open surgery of temporomandibular joint mobilization for the removal of adhesive pseudwalls assisted by arthroscopy, this summary explained the surgical approach by Al-Kayat and Bramley, anatomically important points to remember, indications and treatment results, and procedures and the importance of postoperative rehabilitation.This introduced the diagnostic procedures and treatment algorithm for temporomandibular joint disorders (types IIIb and IV) patients with severe mouth-opening disturbance (mouth-opening distance was less than 30 mm) in the Second Department of Oral and Maxillofacial Surgery, Osaka DentalUniversity. Furthermore, regarding intractable cases whose disease period was more than 6 months and adhesion lesions in the temporomandibular joint were suspected, we evaluated the clinical significance of the open surgery of temporomandibular joint mobilization for the removal of adhesive pseudwalls assisted by arthroscopy as a salvage operation.
著者
久保田 健稔 足立 忠文 山﨑 勝己 小川 倫子 濱田 傑
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.55, no.5, pp.236-240, 2009-05-20 (Released:2012-08-28)
参考文献数
21

We report a rare case of rhinogenous optic neuritis(RON)that was induced by odontogenic maxillarysinusitis in a 34-year-old woman. The patient was referred to our hospital because of visual disturbance of the left eye, gradually developing over the course of 1 month. On presentation to the Department of Ophthalmology, the corrected visual acuity and central critical flicker frequency of the affected left eye was 1.0 and 24Hz, respectively (1.2 and 45 Hz for the right eye). The left eye also showed paracentral scotoma. Computed tomography and magnetic resonance imaging revealed left sphenoid and maxillary sinus opacification, which indicated thickening of these sinus membranes. For a clinical diagnosis of RON in the left eye, a otolaryngologist performed endonasalsphenoid and maxillary sinusotomy under general anesthesia. After sinusotomy the patient came to our department for further evaluation. A panoramic radiograph showed projection of root canal filling material to the left maxillary sinus from the apex of the left maxillary second premolar. We extracted this tooth and the projecting material. Visual symptoms completely resolved 3 months after diagnosis by collaboration among the patient’s ophthalmologist, otolaryngologist, and oral and maxillofacial surgeon.
著者
有岡 将基 佐々木 匡理 石井 広太郎 金本 政樹 山城 崇裕 森 悦秀
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.63, no.1, pp.15-20, 2017-01-20 (Released:2017-03-21)
参考文献数
21

Arsenic trioxide used to be used as an effective endodontic treatment. However, domestic production of arsenic trioxide for mortal pulpectomy was discontinued in 2005, because it is a toxic agent that has the risk of injuring periodontal tissues. We report a case of mandibular osteonecrosis caused by leakage of arsenic trioxide in a child after 2005. The patient was a 6-year-old boy who presented with swelling of the right buccal region, after arsenic trioxide had been used for mortal pulpectomy in the mandibular right second primary molar. The condition was diagnosed as mandibular osteonecrosis. The mandibular right first primary molar and mandibular right second permanent premolar were extracted, and a sequestrectomy was performed with the patient under local anesthesia. We still should consider that leakage of pulp devitalizing agents can cause osteonecrosis.
著者
住吉 周平 南部 敏之 本田 武司 下田 恒久 宮島 陽一 堤 定美
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.42, no.12, pp.1192-1199, 1996-12-20 (Released:2011-07-25)
参考文献数
21
被引用文献数
4 1

Although mouthguards are used to protect the stomatognathic region in contact sports, their biomechanical efficacy has not been proved. The finite element method (FEM) is widely used in biomechanical studies involving static stress analyses. Studies of mouthguards especially require dynamic analyses. We performed an impact analysis of the maxillofacial region with the use of a pseudo 3 -D FEM model consisting of the head and neck in order to verify the efficacy of two mouthguard models against impact on the chin.The effects of impact on the maxillary central incisors and the neck of the condyle increased remarkably when the mouth was open. With the use of a mouthguard, the efficacy of impact absorption extended to the maxillary central incisors and the lateral margin of the aperture. A soft-type mouthguard was more effective than a hard-type one. With the use of a mouthguard, stress was concentrated at the neck of the condyle. The use of a mouthguard decreased stress to regions adjacent to the cerebrospinal area. These results suggest that mouthguards are effective in preventing brain concussion.
著者
大関 悟 大部 一成 田代 英雄
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.33, no.3, pp.627-634, 1987-03-20 (Released:2011-07-25)
参考文献数
16
被引用文献数
1 1

Thermotherapy by 2450 MHz microwaves was performed on oral cancer patients and its effectiveness was analyzed and evaluated.Subjects were 7 primary oral cancer patients (4 lower gum cancer, 2 buccal mucosa and 1 oral floor) and 5 recurrent cancer patients (3 with cheek lesion and 2 with neck lesion). Heat was generated by a microwave apparatus of 2450 MHz.Seven cases which received intraoral thermotherapy on primary lesions were treated in combination with radiation and bleomycin. Thermotherapy was performed twice a week, up to 5-8 times in total, applyied immediately after the radiation therapy. Intraoral applicator was a flexible leakage-type coaxial applicator 2-4 mm in diameter and 40-90 mm in length. It was modified depending on each tumor size and shape. Tumor surface was heated to 42-45°C for 30-50 minutes and the heat distribution pattern of each modified applicator was checked using Phantom Model. Of the seven lesions, 6 (85.7%) showed complete regression (CR) and one showed partial regression (PR). Histological examination was made on five cases which received surgical tumor resection. Among them, one was grade III and the rest were grade IIb by Simosato's criteria. Tumor necrosis and mucosal reaction were seen at the heated site from the early stage of treatment and the thermotherapy was obviously effective.Five recurrent cancer patients received extraoral thermotherapy without radiotherapy on the cheek or neck lesions using the non-contact type applicator. Tumor necrosis was limited to the surface area and the regression effect was minimum which might be due to the lack of combination therapy of radiation.Thermotherapy seemed effective for the oral cancer when used in combination with radiation. However, more clinical experience is needed to evaluate the usefullness of this treatment.
著者
立石 晃 天野 裕治 相田 高幸 福田 仁一
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.48, no.8, pp.423-426, 2002-08-20 (Released:2011-04-22)
参考文献数
10

A case of non-clostridial gas gangrene with sepsis in the maxillofacial region and neck caused byodontogenic infection is reported.A 74-year-old woman consulted our department because of painful swellingof the head and neck region.She had been treated for depression for about 20 years.Her general conditionwas classified as I-2 coma according to the Japan coma scale.Blood examination revealedleukocytosis, hepatopathy, nephropathy, hypoalbuminemia, and hyperglycemia.A computed tomographicscan showed gas accumulation with abscess formation in the temporal, buccal, submandibular, and cervicalregions.Administration of antibiotics (PAPM/BP) and gamma-globulin was followed by emergencysurgical drainage under general anesthesia. Microbiological examinations revealed Streptococcus pneumoniae in the abscess and Peptococcus asaccharolyticus in venous blood on the 1st disease day. Aftertreatment, the swelling disappeared and the results of blood tests became normal.However, a secondmicrobiological examination of venous blood also revealed Peptococcus asaccharolyticus on the 9 th diseaseday. Antibiotics (CLDM) were given from the 17th to 20th disease days.Hyperglycemia was controlledby insulin.She was discharged on the 53rd disease day.Rapid diagnosis by computed tomography, rapid surgical drainage, appropriate chemotherapy, and examinationsof blood cultures and for DIC are required to save patients'lives.
著者
石川 義人 樋口 雄介 青村 知幸 八木 正篤 遠藤 光宏 笹原 健児 佐藤 雄治 大屋 高徳 工藤 啓吾
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.44, no.4, pp.415-417, 1998-04-20 (Released:2011-07-25)
参考文献数
6
被引用文献数
5 3

We studied the cause, status, and treatment of temporomandibular joint (TMJ) dislocation in patients with psychic and cerebral diseases. These diseases were present in 11 (26.2 %) of 42 patients with TMJ dislocation. Psychic disease included 2 cases of mental retardation and 3 of schizophrenia. Cerebral diseases included 1 case of cerebral infarction, 3 of cerebral hemorrhage, 1 of epilepsy, and 1 of Parkinson disease. There were many old patients among those with cerebral diseases. Convulsions characteristically led to TMJ dislocation. There was prolonged dislocation of the TMJ. A reliable treatment was required in patients with these diseases. Therefore, augmentation of the articular tubercle was indicated. It was suggested that incoordination of the masticatory muscles induced TMJ dislocation. Furthermore, extrapyramidal disorders may have been caused by antipsychotic drugs, Parkinson disease, and cerebrovascular disease; convulsions due to epilepsy may lso have been involved.
著者
太田 信介 松井 義郎 福留 文乃 海野 智 大村 進 藤内 祝
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.53, no.10, pp.623-627, 2007-10-20 (Released:2011-04-22)
参考文献数
12
被引用文献数
1

Although varicella zoster virus (VZV) infection commonly occurs in the oral and maxillofacial region, tooth exfoliation and alveolar osteonecrosis are relatively rare complications. We describe two cases of tooth exfoliation and alveolar osteonecrosis caused by VZV infection of the trigeminal nerve and review the literature. A 66-year-old man and a 38-year-old man were referred to our hospital because of tooth exfoliation. The first patient had a history of spinocerebellar degeneration, and the second had a history of chronic myelogenous leukemia. Tooth exfoliation occurred on day 21 and day 25 after the onset of VZV infection, respectively. Clinicopathological examination in the first patient revealed actinomyces infection. Panorama x-ray films obtained previously in the second patient revealed no evidence of severe periodontal disease before VZV infection. These findings suggested that tooth exfoliation and osteonecrosis by VZV infection were not only caused by existing severe dental infectious disease, but also by various factors such as multiple oral bacteria, tissue reaction to VZV infection, and compromised status.