著者
若林 健 竹内 憲民 楠山 友紀子 山本 汐里 文元 玲子 由良 義明
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.61, no.8, pp.424-428, 2015-08-20 (Released:2015-11-24)
参考文献数
10
被引用文献数
1 1

We report a case of extensive bisphosphonate-related osteonecrosis of the jaw (BRONJ) associated with a mandibular fracture, which improved after treatment with teriparatide and surgical therapy. An 83-year-old woman was referred to our hospital because of swelling of the submandibular region. At presentation, clinical examination revealed swelling of the right submandibular region and discharge of pus. A computed tomographic (CT) scan confirmed osteolytic changes and a fracture of the mandible. Three months after bone curettage, fixation with a titanic plate, and treatment with teriparatide, new bone formation was observed. Five months after this therapy, the fractured segment had completely healed. Teriparatide may contribute to the improvement of BRONJ.