著者

坂口 一夫 岩田 由美 堀内 暢子 市川 秀一

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.30, no.5, pp.326-329, 2004-05-10 (Released:2011-03-04)

参考文献数

14

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Iron is known to interact with various foods and drugs taken at the same time and since ascorbic acid generally seems to promote the intestinal absorption of iron, we performed a retrospective medical survey using medical charts to establish the effect of ascorbic acid on patients with iron deficiency anemia taking sodium ferrous citrate. The hemoglobin levels and hematocrits of patients with iron deficiency anemia were markedly improved after taking sodium ferrous citrate containing 50 mg of elemental iron alone for 4 to 8 weeks. However, there was no difference between the hemoglobin and hematocrit results for this group of patients and another group who took ascorbic acid (200mg) in addition to sodium ferrous citrate. These results suggest that ascorbic acid does not influence the efficacy of sodium ferrous citrate when these agents are administered together for the treatment of iron deficiency anemia.

著者

八木 俊一 市川 秀一 酒巻 哲夫 高山 嘉朗 村田 和彦 菅井 芳郎

出版者

一般社団法人 日本動脈硬化学会

雑誌

動脈硬化 (ISSN:03862682)

巻号頁・発行日

vol.15, no.1, pp.205-208, 1987-04-01 (Released:2011-09-21)

参考文献数

5

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We usually measure blood pressure of hemiparetic stroke patients with the intact upper arm. It is unclear whether the values of blood pressure of the paretic arms are higher or lower than those of the intact contralateral arms. Simultaneous measurements of blood pressure of bilateral arms of stroke patients were carried out using two automatic manometers in the present study.Subjects were forty-seven stroke patients in chronic phase. Thirty patients were diagnosed as cerebral hemorrhage and seventeen were the patients with cerebral infarction. Twenty patients had right hemiparesis and twenty-seven patients were with left hemiparesis. The patients were supine position for fifteen minutes before measurement of blood pressure. Blood pressure of bilateral arms was determined by inflating simultaneously cuffs after these of the two automatic manometers (TAKEDA MEDICAL, UA-254) attached to the both sides. Measurements were performed three times successively every minute, the manometers were changed with each other and three more determinations were carried out. The mean values for these six measurements were compared in each side of the paretic and intact arms. For the comparison of the thickness of each arm, we measured the circumference of bilateral arms at the 5cm proximal point from the elbow joint. P value of <0.05 was considered significant.Blood pressure of the paretic arm was 131±3mmHg (mean ± SE) in systolic and 83±1mmHg in diastolic. Blood pressure of the intact arm was 129±3mmHg in systolic and 78±1mmHg in diastolic. Both systolic and diastolic blood pressure of the paretic arm were significantly (p<0.01 and p<0.001 respectively) higher than those of the intact arm. The circumference of the paretic arm did not differ from that of the intact arm (21.6<0.3cm versus 21.9<0.3 cm).Because we have often observed muscle atrophy or edema in paretic extremities of stroke patients, the difference of blood pressure could be expected between the paretic and intact arm. In this study, both systolic and diastolic blood pressure of the paretic arm were higher than those of the intact arm. The difference of blood pressure does not seem to arise from unfitness of width of manometer's cuff for arm thickness since the thickness of paretic arm did not differ from that of intact arm.