著者

平賀 幸弘 黄 淳一

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.106, no.4, pp.341-346, 2013 (Released:2013-04-01)

参考文献数

21

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Anaplastic thyroid carcinoma is a rare and lethal human malignancy. In this paper, we report on a case of a 55-year-old man who had undergone radiation therapy on the cervical region for malignant lymphoma at 14 years of age, and had been consulting our hospital for 19 years. He underwent a left hemithyroidectomy for papillary thyroid carcinoma at the age of 35, and 11 years after that a total thyroidectomy was performed for cervical nodal disease. After the operation he underwent radioiodine therapy twice. Five years after radiotherapy, anaplastic carcinomas arose in the left cervix and the cranium. Soon after complete resections of the tumors, systemic metastases were detected with FDG-PET. Finally, 11 months after the operation, he died in our palliative care unit at the age of 55 due to frequent bleeding from a palatal carcinoma. A review of the literature showed that the age at which the tumor arose, namely the peak of the patient’s life, was earlier than was usually reported. The survival time of 11 months observed in our patient was more than that generally observed in patients with anaplastic carcinoma.

著者

平賀 幸弘 黄 淳一 霜村 真一

出版者

一般社団法人 日本耳鼻咽喉科頭頸部外科学会

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.116, no.10, pp.1114-1119, 2013-10-20 (Released:2013-11-26)

参考文献数

12

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血管免疫芽球性T細胞リンパ腫 (angioimmunoblastic T-cell lymphoma: AITL) の1症例を経験した. 患者は33歳女性で, 前頸部に単発の腫瘤を認め, 手術にて摘出された. 病期診断はStage IAで, CHOP3コースと頸部へのX線照射40Gyが施行され, 経過観察中であるが再発を認めない. AITLは, 非ホジキンリンパ腫の1.2~2.5%にみられるまれな疾患で, 耳鼻咽喉科領域での報告は認めない. 全身リンパ節腫脹, 肝脾腫, 皮疹, 貧血, 高ガンマグロブリン血症などを症状とする. 治療は多剤併用の化学療法が一般的であるが, 5年生存率20~50%と高悪性に分類されている.