1 0 0 0 OA α-クロロスルフィドを用いる有機合成
- 著者
- 新井 和孝
- 出版者
- The Society of Synthetic Organic Chemistry, Japan
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.39, no.5, pp.374-384, 1981-05-01 (Released:2009-11-13)
- 参考文献数
- 70
- 被引用文献数
- 5 6
In recent years, α-chlorosulfides have been utilized as very useful synthetic intermedites. Firstly, in this article, the preparation methods of α-chlorosulfides are reviewed, and the critical points of the preparative reactions are summerized as follows : (1) selectivity of degree of the chlorination, (2) α, β-elimination of hydrogen chloride, (3) cleavage of C-S bond of sulfides, and (4) regioselectivity of the chlorination. Secondly, many types of the reaction of α-chlorosulfides are introduced together with each typical application in organic synthesis, classified in three groups, (1) the reactions with nucleophiles, (2) the reactions as electrophiles, and (3) miscellaneous reactions.The scope and limitation of the synthetic utility of the reaction of α-chlorosulfides will be clarified in this review.
1 0 0 0 OA 異性化晶出法を利用した光学分割
- 著者
- 新井 和孝
- 出版者
- The Society of Synthetic Organic Chemistry, Japan
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.44, no.6, pp.486-498, 1986-06-01 (Released:2010-01-22)
- 参考文献数
- 52
- 被引用文献数
- 4 8
In recent years, synthetic method by the combination of isomerization and crystallization is studied intensively, especially in the practical optical resolution. In this paper, this isomerization-crystallization method is introduced from a point of view of practical organic synthesis. A number of examples of this isomerization-crystallization method in optical resolution, many of which were often reported as the example of second-order asymmetric transformation phenomena, are classified into following two groups, and reviewed.(1) Epimerization-crystallization method.(2) Racemization-preferential crystallization method.The potentialities and difficulities of each method are also discussed. The compounds resolved by this methods are α-amino acid derivatives, cyanohydrin derivatives, α-aromatic carboxylic acid esters, and so on.
1 0 0 0 異性化晶出法を利用した光学分割
- 著者
- 新井 和孝
- 出版者
- 社団法人 有機合成化学協会
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.44, no.6, pp.486-498, 1986
- 被引用文献数
- 8
In recent years, synthetic method by the combination of isomerization and crystallization is studied intensively, especially in the practical optical resolution. In this paper, this isomerization-crystallization method is introduced from a point of view of practical organic synthesis. A number of examples of this isomerization-crystallization method in optical resolution, many of which were often reported as the example of second-order asymmetric transformation phenomena, are classified into following two groups, and reviewed.<BR>(1) Epimerization-crystallization method.<BR>(2) Racemization-preferential crystallization method.<BR>The potentialities and difficulities of each method are also discussed. The compounds resolved by this methods are α-amino acid derivatives, cyanohydrin derivatives, α-aromatic carboxylic acid esters, and so on.