著者
丸田 雅樹 末盛 浩一郎 谷脇 真潮 村上 忍 福島 万奈 加藤 潤一 木原 久文 名部 彰悟 池田 祐一 越智 俊元 波呂 卓 谷本 一史 竹内 一人 山之内 純 宮本 仁志 竹中 克斗
出版者
一般社団法人 日本感染症学会
雑誌
感染症学雑誌 (ISSN:03875911)
巻号頁・発行日
vol.96, no.4, pp.148-153, 2022-07-20 (Released:2022-07-20)
参考文献数
17

A 69-year-old male was admitted to Ehime University Hospital with bicytopenia. He was diagnosed with myelodysplastic syndrome (MDS) and was administered chemotherapy. He was a multimorbid patient with chronic kidney disease (CKD), chronic obstructive pulmonary disease (COPD), type 2 diabetes, and Sweet's disease resulting in a skin rash. The patient was treated with oral prednisolone for Sweet's syndrome, and cefepime infusions for pneumonia that arose during the first course of chemotherapy. Both of these complications were almost recovered on physical and image findings. During the second course of chemotherapy, he developed Kytococcus schroeteri bacteremia that was successfully treated with linezolid and meropenem infusions, but he died owing to Stenotrophomonas maltophilia bacteremia that occurred 6 h after the K. schroeteri bacteremia. Postmortem microbiology (PMM) proved his reservoir of S. maltophilia bacteremia as pneumonia. There are only 20 reports of K. schroeteri bacteremia in the Medline database. According to our knowledge, this is the first case that developed K. schroeteri and S. maltophilia bacteremia sequentially. In addition, this case highlights the importance of PMM in improving treatment of infectious diseases.
著者
末盛 浩一郎 安川 正貴
出版者
愛媛大学
雑誌
基盤研究(C)
巻号頁・発行日
2019-04-01

重症熱性血小板減少症候群(Severe fever with thrombocytopenia syndrome; SFTS)は2011年に中国で初めて報告された新興感染症である。我が国でも2013年に初めて患者が確認され、致死率が10~30%と極めて高い。有効な治療法が確立されておらず、病態解明と治療法の確立は喫緊の課題である。本研究の目的は臨床像の病態解明により予後改善を目指すことである。