著者

吉田 真平 藤田 真敬 大塚 康民 柳田 保雄 柏崎 利昌 田村 敦 別宮 愼也 森本 浩吉

出版者

航空医学実験隊

雑誌

航空医学実験隊報告 (ISSN:00232858)

巻号頁・発行日

vol.58, no.3, pp.27-40, 2018 (Released:2018-11-27)

参考文献数

75

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In Japan, “hay fever”, seasonal allergic rhinitis caused by pollen, has become more popular and has been called national affliction. Although there are less serious symptoms of hay fever, symptoms including sneezing, runny nose and itchy eye, sleep impairment, fatigue, impairment of learning and cognitive performance, have potential safety risks for flying or driving. The usage of some medications such as anti-histamines with less adverse effects on central nervous system, are approved for pilots under an appropriate regulation. However, the criteria of approval and conditions in the regulations differs from organizations in countries. In this article, we summarize current medications for “hay fever” including antihistamines, montelukast, subcutaneous and sublingual immunotherapy. We also compare aeromedical regulations for these medications between Japan and U.S.. The immunotherapy, minimizing allergic reaction for “hay fever”, may be one of the potential option for pilots.

著者

金澤 富美子 菊川 あずさ 金丸 善樹 髙澤 千智 大類 伸浩 丸山 聡 柳田 保雄 小林 朝夫 柏崎 利昌 藤田 真敬

出版者

航空医学実験隊

雑誌

航空医学実験隊報告 (ISSN:00232858)

巻号頁・発行日

vol.57, no.1, pp.1-13, 2017 (Released:2017-05-25)

参考文献数

17

被引用文献数

2

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Pilot fatigue, which causes 21% incidents in US Civil Aviation, 25% lethal accidents in US Air Force's night tactical flight, and 12% lethal accident in US Navy, has been recognized as an insidious threat through out aviation. Despite our recognition of fatigue, no guideline was published until 2011, due to its difficulty in objective assessment. Recently, objective assessment for fatigue has been partly established and contributed to open guidelines. National Institute for Occupational Safety and Health (NIOSH) published guidebook as "Plain language about shiftwork" in 1997. Aerospace Medical Association published position paper as "Fatigue countermeasures in aviation" in 2009. International Air Transport Association (IATA), International Civil Aviation Organization (ICAO), and International Federation of Air Line Pilots’Association (IFALPA) published "Fatigue Risk Management System (FRMS) Implementation guide for operators" in 2011. Those guidelines says that aviation-related fatigue is caused by disorder of sleep and circadian rhythm. Psychomotor Vigilance Task (PVT) or Motion logger watch (Actigraphy) are recommended for objective assessment of fatigue. Best counter measures for shift work and aviation related fatigue are adequate sleep. We review those guidelines and discuss applicability for safe flight in Japan Air Self-Defense Force.

著者

高澤 千智 藤田 真敬 小林 朝夫 大塚 康民 鳥畑 厚志 大類 伸浩 高田 邦夫 立花 正一 柏崎 利昌 別宮 愼也

出版者

航空医学実験隊

雑誌

航空医学実験隊報告 (ISSN:00232858)

巻号頁・発行日

vol.56, no.3, pp.67-77, 2016 (Released:2020-04-11)

参考文献数

45

被引用文献数

1

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It has been issued that many accidents are caused by impaired driving or impaired flying due to side effects of medications. In 2013, US Federal Aviation Agency (FAA) warned about aircraft accidents due to side effects of medications. Japan Ministry of Internal Affairs and Communications (JMIAC) also made recommendations to Japan Ministry of Health, Labor and Welfare (JMHLW) to confirm notification about driving ban in the patient package insert. The aviators who use an impairing medication are required to wait an appropriate periods after last medications before flying. FAA defines a waiting time from last medications to flight as five times of pharmaceutical half-lives. Japan Ministry of Land, Infrastructure, Transport and Tourism (JMLIT) also defines as two times the dosing interval. The dosing interval is generally determined by pharmaceutical half-lives. Considering above situations, Japan Air Self-Defense Force, Aeromedical Laboratory (JASDF AML), recommends a waiting time from last medications to flight as five times of pharmaceutical half-lives. Newly marketed medications are monitored through post-marketing surveillance and reviewed qualification for aviators. Monitoring periods are three years or more in US Air Force, but one year in FAA, JMLIT and JASDF. We review aeromedical decision making for the safe flight with medicated aviators and related articles.