著者
齊藤 昌樹 畑中 隆志 川口 拓郎 久馬 孝仁 長嶺 健二郎 澤木 佳弘
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.61, no.12, pp.667-672, 2015-12-20 (Released:2016-03-14)
参考文献数
34
被引用文献数
1 5

Recently, methotrexate-associated lymphoproliferative disorders (MTX-LPD) in patients with rheumatoid arthritis (RA) have frequently been reported as a lymphoproliferative disorder developing in immunosuppressed patients. Many reports have indicated a relation between MTX-LPD and Epstein-Barr virus (EBV). We report 4 cases of EBV-positive MTX-LPD arising in the oral cavity. After consulting a hematologist, methotrexate (MTX) was discontinued in three patients, and one patient moved to another medical facility. Three lesions regressed after MTX withdrawal. However, one patient who resumed treatment with MTX had a relapse of LPD. A literature search on MTX-LPD in the oral cavity revealed a high positive rate of EBV, a good response to MTX withdrawal, a higher prevalence in women, and a high frequency of maxillary gum involvement.
著者
萩野 浩子 澤木 佳弘 小田 知生 孫田 亜希子 村田 香織 上田 実
出版者
特定非営利活動法人 日本口腔科学会
雑誌
日本口腔科学会雑誌 (ISSN:00290297)
巻号頁・発行日
vol.49, no.5, pp.271-277, 2000-09-10 (Released:2011-09-07)
参考文献数
19
被引用文献数
1

The purpose of this study was to investigate the postoperative one-year positional change following Intraoral Vertical Ramus Osteotomy (IVRO). Retrospective radiographic assessments were performed on 43 patients who underwent bilateral IVRO to setback without interosseous fixation.The results were as follows:1. No relationship was observed between the openbite and the mandibular displacement during postoperative treatment for one year. In addition, no relationship was observed between the amount of mandibular displacement following surgery and that during postoperative treatment for one year.2. The postoperative mandibular position following IVRO was stable, and this method was effective to correct mandibular protrusion.