1 0 0 0 OA Polonovski反応の合成化学への応用
- 著者
- 池田 正澄 田村 恭光
- 出版者
- The Society of Synthetic Organic Chemistry, Japan
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.38, no.1, pp.10-21, 1980-01-01 (Released:2009-11-13)
- 参考文献数
- 78
- 被引用文献数
- 6 10
The synthetic utility of the Polonovski reaction has recently been widely explored. Besides classical use in dealkylation of tertiary amines and in the preparation of enamines, it can also be used in the syntheses of a Mannich reagent and many indole alkaloids. Success in the syntheses of vinblastine and related compounds is one of the most important developments. The present review summarizes the synthetic applications of this reaction.
1 0 0 0 OA シリルケテンアセタールを用いる有機合成反応
- 著者
- 北 泰行 田村 修 田村 恭光
- 出版者
- The Society of Synthetic Organic Chemistry, Japan
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.44, no.12, pp.1118-1133, 1986-12-01 (Released:2009-11-13)
- 参考文献数
- 201
- 被引用文献数
- 12 16
Silyl ketene acetals (SKA) have attracted much attention as useful synthetic reagents. This review deals with the recent studies (mainly after 1980) on the preparations and reactions utilizing SKA in the following items with 147 references; [1] Preparations; a) general preparation, b) selective synthesis of E- and Z- SKA. [2] Reactions; a) protonation, b) oxidation, c) electrophilic substitution, d) cycldaddition, e) sigmatropic reaction, f) others.
1 0 0 0 OA アントラサイクリン系抗生物質の合成研究
- 著者
- 田村 恭光 北 泰行
- 出版者
- The Society of Synthetic Organic Chemistry, Japan
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.46, no.3, pp.205-217, 1988-03-01 (Released:2009-11-13)
- 参考文献数
- 57
- 被引用文献数
- 11 13
Anthracycline antibiotics are important antitumor agents in clinical use and much attention has been paid to the synthesis of these antibiotics and related compounds. In this article, authors explain new and facile cycloadditions of homophthalic anhydrides and application of these reactions to highly regiospecific syntheses of naturally occurring anthracycline antibiotics and related anthracyclines. This review contains the following items with 57 references; [1] Cycloaddition of homophthalic anhydrides; a) thermal cycloaddition, b) strong base-induced cycloaddition. [2] Synthesis of anthracyclines; a) 4-demethoxydaunomycin and daunomycin, b) 11-deoxydaunomycin, c) adriamycin-type anthracycline, d) optically active anthracyclinone, e) amino sugars. [3] Synthesis of D-ring heteroaromatic analogues of anthracyclines.