著者
中尾 英雄 福島 正美 清水 総明 荒川 順生
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.94, no.8, pp.1032-1037, 1974-08-25 (Released:2008-05-30)
参考文献数
6
被引用文献数
12 14

Water-soluble derivatives of N-(2-chloroethyl)-N-nitrosourea were synthesized and their antitumor activity was tested against leukemia L-1210. Most of these compounds showed a high activity.
著者
中尾 英雄 荒川 順生 中村 隆洋 福島 正美
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.20, no.9, pp.1968-1979, 1972-09-25 (Released:2008-03-31)
被引用文献数
24 31

A series of 2, 5-bis (1-aziridinyl)-p-benzoquinone derivatives were synthesized and evaluated as antileukemic agents. The most active compounds against lymphoid leukemia L-1210 in BDF1 mice were 2, 5-bis (1-aziridinyl)-3-(2-carbamoyloxyethyl-1-methoxy)-6-methyl-p-benzoquinone, carbazilquinone (7), and related compounds (8, 23 and 24). Structure-activity relationships were discussed.
著者
中尾 英雄 福島 正美 菅原 眞一
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.93, no.11, pp.1526-1529, 1973-11-25 (Released:2008-05-30)
参考文献数
5
被引用文献数
2 2

5-Cyano-2-furaldehyde and its derivatives were synthesized and their antimicrobial activities were tested. Neither series of compound possessed significant antimicrobial activity.