著者

篠原 治征 杉浦 正

出版者

社団法人 日本口腔外科学会

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.62, no.2, pp.100-104, 2016-02-20 (Released:2016-04-20)

参考文献数

17

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A 34-year-old woman was referred to our department because of trismus. Physical examination showed severe trismus and stiffness of the masseter muscles. She had a miscarriage in the Philippines a few days ago, received treatment, and went back to Japan. Maternal tetanus( MT) was diagnosed on the basis of the clinical course and symptoms. The patient was immediately admitted to the intensive care unit. She was given anti-tetanus human immunoglobulin and antibiotics. The patient recovered without undergoing a tracheotomy or tracheal intubation. The World Health Organization( WHO) has reported that maternal and neonatal tetanus( MNT) has decreased in developing countries. However, delivery and miscarriage in an insanitary environment remain a problem. Tetanus is a fatal infectious disease if early treatment is not appropriately performed. An early warning symptom of tetanus is trismus. Patients with this disease may therefore initially consult a dentist or an oral surgeon. We should consider the possibility of tetanus when examining patients with trismus and observe them carefully.

著者

櫻井 賢 小野 徹 天内 孝昌 篠原 治征 戸谷 収二 田中 彰 又賀 泉

出版者

JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.24, no.1, pp.7-12, 2005-04-01 (Released:2010-06-08)

参考文献数

10

被引用文献数

1

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Pseudomonas aeruginosa has been frequently detected from sputa around tracheostomy stuma with a high frequency of nosocomial infection among patients with an opportunistic infection. It is also reported to be difficult to treat lower respiratory infections when resistance to antibiotics for Pseudomonas aeyuginosa has developed. We discuss 15 patients, (8 males and 7 females) who underwent tracheostomy and in whom Pseudomonas aeyuginosa was isolated for 10 years from April 1993 to March 2003. Average age was 62.0 years old. All subjects were oral cancer patients. Pseudomonas aeyuginosa was detected from cultures in 15 of 19 patients (78.9%) . It was isolated from and had colonized the lower respiratory tract by 34.6 days on average after tracheostomy. Gradual change of sensitivity to antiobiotics and increase of drug tolerance were recognized. As drug tolerance may be affected by long-term administration of antibiotics, selection of antibiotics and period should be carefully considered to avoid the development of tolerance.