著者
西川 正子
出版者
日本計量生物学会
雑誌
計量生物学 (ISSN:09184430)
巻号頁・発行日
vol.29, no.2, pp.141-170, 2008-12-01 (Released:2011-09-15)
参考文献数
73
被引用文献数
2 1

The statistical analysis of survival time or failure time data is an important topic in many areas of research. In ordinary survival data, there is a single, possibly right-censored failure time for each individual. However, in a number of medical applications whereby data is collected an individual may experience one or more events but the first event will preclude the occurrence of another event under investigation. As a result, he/she can experience only one of several types of events. Such data are commonly referred to as competing risks data. Censoring due to such an event is generally not independent of the time to the event of interest.This paper reviews statistical methods for analyzing a competing risks model. Both conceptual considerations and common approaches to one-sample inference; two sample comparison; and covariate effect modeling are discussed. The theory for the analysis of ordinary right-censored survival data can be applied under certain circumstances. Standard statistical software package can perform the necessary analysis, although interpretation of results will vary.
著者
福島 東浩 澁谷 有香 小林 秀嗣 西川 正子 庄司 和広
出版者
日本臨床麻酔学会
雑誌
日本臨床麻酔学会誌 (ISSN:02854945)
巻号頁・発行日
vol.39, no.1, pp.1-8, 2019-01-15 (Released:2019-02-14)

セボフルラン(SEV)よりもデスフルラン(DES)の方が早く覚醒するといわれるが,実臨床では吸入麻酔の種類より麻酔科医の熟練度の方が影響を与えている可能性がある.本研究の多変量解析の結果,抜管までの時間はDES使用より(HR 1.17,[95%信頼区間 1.01-1.34],p=0.04),麻酔科医の熟練度の方が強く関連していた(研修医+指導医;参照,卒後6-9年;HR 1.59,[1.24-2.05,p<0.001],卒後10年;HR 1.53,[1.20-1.97,p=0.001]).抜管までの時間はDES使用で若干の短縮が認められたが,麻酔科医の熟練度の影響の方が大きいことが示唆された.