著者

三宅 志穂 井内 希 木戸 彩也香 熊田 愛 大山 紗絵子 佐々木 晶子 Shiho MIYAKE Nozomi IUCHI Sayaka KIDO Mana KUMATA Saeko OOYAMA Akiko SASAKI

雑誌

神戸女学院大学論集 = KOBE COLLEGE STUDIES

巻号頁・発行日

vol.57, no.1, pp.125-132, 2010-06-30

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According a research in the brain science research field. it was suggested that foreign people recognized the sound of insects as noise. However, Lafcadio Hearn from Greek admired the sound of the cicada. Therefore, it is supposed that some other nations as well as the Japanese can sympathize with the sound of insects. In this research, a pilot survey about the impression of "like" or "dislike" on the sound of insects was conducted for the Japanese and other nations. Field interview to the Japanese and foreign visitors to Japan was carried out in Kyoto from July to November, 2009. Answers by "like" or "dislike" of the impression from 450 foreigners and 100 Japanese people were obtained on the sound of five sorts of insects: Teleogryllus emma, Oncotympana maculaticollis, ampsocleis buergeri, Homoeogryllus japonicus, Tanna japonensis. People in the total of 35 nations cooperated in this research. As a result, it was suggested that the impression on the sound of five insects between foreign people and Japanese people had similarity. On the other hand, the ratio of the number of people, who answered "like" or "dislike", was defferent between foreign countries and Japan. Furthemore, the following issues were understood by the result from nine foreign nations, where the samples of ten or more people were collected. 1) The impression of "like" or "dislike" on the sound of insects would be different from each nation. It cannot be caught only by a framework of Jspsnrdr people and foreign people. 2) Distinction of "like" or "dislike" cannot be relevant to the sound by one concept of "insects". That is, impression of the sound may depend on the kind of the insect.

著者

Miki Nagata Mayumi Tsuji Tatsunori Oguchi Yutaro Momma Tetsuhito Nohara Hideaki Ohashi Naohito Ito Ken Yamamoto Yuko Udaka Akiko Sasaki Yuji Kiuchi Satoshi Numazawa

出版者

The Pharmaceutical Society of Japan

雑誌

BPB Reports (ISSN:2434432X)

巻号頁・発行日

vol.4, no.6, pp.206-213, 2021 (Released:2021-12-27)

参考文献数

41

被引用文献数

2

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Dementia is expected to affect an increasing number of patients with global aging populations. About 70% of all dementia is related to Alzheimer's disease (AD). Overaccumulation of amyloid-β protein (Aβ) in the brain forms senile plaques, one of the main features of neurodegeneration in AD. However, there are few drugs available to specifically inhibit senile plaque formation. Fucoidan, a sulfated polysaccharide derived from brown algae, has various bioactivities, such as anti-tumoral and anti-obesity effects. This study aimed to clarify the mechanism underlying the protective effect of fucoidan against Aβ-induced neurotoxicity in human neuroblastoma SH-SY5Y cells. Cell viability and Aβ-induced cytotoxicity were measured by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, calcein AM, and ethidium homodimer-1. Aβ-induced oxidative stress was evaluated through reactive oxygen species (ROS), cell membrane phospholipid peroxidation, mitochondrial ROS, and Mn-SOD, a mitochondrial radical scavenger. In addition, mitochondrial membrane permeability transition, and ATP concentration were evaluated. Fucoidan significantly improved Aβ-reduced cell viability. With respect to oxidative stress, Aβ exposure increased ROS, lipid peroxidation, and mitochondrial ROS, while fucoidan significantly suppressed these changes. Fucoidan also suppressed the decline in mitochondrial permeability transition and ATP caused by Aβ. Therefore, through its numerous antioxidant activities, fucoidan might have a neuroprotective role in preventing Aβ-induced neurotoxicity.

著者

Kosuke Tanaka Akiko Sasaki Hideto Egashira Shinichi Teshima Karen Kimura Takashi Nishino Tomohiko Tazawa Junichi Tasaki Chikamasa Ichita Sakue Masuda Kazuya Koizumi Makoto Kako

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.60, no.7, pp.999-1004, 2021-04-01 (Released:2021-04-01)

参考文献数

21

被引用文献数

2

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We herein report the definitive diagnosis of rectovaginal endometriosis in two cases. Case 1 involved a 46-year-old woman with abdominal pain and hematochezia. The diagnosis after the first and second examinations using lower gastrointestinal (GI) endoscopy was unclear. Differential diagnoses included mucosa-associated lymphoid tissue and colorectal cancer. The third lower GI endoscopy with a targeted biopsy, performed during menstruation, confirmed rectovaginal endometriosis. Case 2 involved a 38-year-old woman with hematochezia. Lower GI endoscopy during menstruation revealed rectovaginal endometriosis. When rectovaginal or bowel endometriosis is suspected, lower GI endoscopy and a targeted biopsy during menstruation can prevent unnecessary surgery.