- 著者
- 佐藤 千晶 吉田 仁美 Chiaki SATO Hitomi YOSHIDA
- 出版者
- 昭和女子大学近代文化研究所
- 雑誌
- 学苑 = Gakuen (ISSN:13480103)
- 巻号頁・発行日
- no.964, pp.104-111, 2021-02-01
A Study of Childcare Problems for a Hearing Impaired Couple: Research Analysis Using the Trajectory Equifinality Model (TEM)Chiaki SATO and Hitomi YOSHIDAAs part of the effort toward child-rearing support in Japan, the reform of men’s work styles has gained attention, in addition to support for women’s work-family balance. However, child-rearing support for parents with disabilities is far from sufficient.Through a qualitative survey administered to a child-rearing husband and a wife with hearing impairment, this article aims to reveal issues in their lives and to explore how child-rearing support should be provided for parents with disabilities. The results were analyzed using the Trajectory Equifinality Model (TEM). The analysis revealed that close support from the wife’s side of the family was critical for the hearing impaired couple in raising children. Further, issues regarding future child-rearing support included the following: first, accessibility to essential child-rearing support service for people with hearing impairment; second, support measures that do not depend on the families of child-rearing parents must be sought; third, companies must undergo fundamental reform regarding working conditions and attitudes toward work; finally, family-friendly local communities must be fostered.
- 著者
- Chiaki SATO Saki KANEKO Ayami SATO Nantiga VIRGONA Kozue NAMIKI Tomohiro YANO
- 出版者
- Center for Academic Publications Japan
- 雑誌
- Journal of Nutritional Science and Vitaminology (ISSN:03014800)
- 巻号頁・発行日
- vol.63, no.5, pp.349-354, 2017 (Released:2017-12-08)
- 参考文献数
- 29
- 被引用文献数
- 9 26
Tocotrienols (T3s) and tocopherols (Tocs) are both members of the vitamin E family. It is known that δ-tocotrienol (δ-T3) has displayed the most potent anti-cancer activity amongst the tocotrienols. On the other hand, γ-tocopherol (γ-Toc) is reported to have a protective effect against prostate cancer. Therefore, we investigated whether the combination of γ-Toc and δ-T3 could strengthen the inhibitory effect of δ-T3 on prostate cancer cell growth. In this study the effect of combined δ-T3 (annatto T3 oil) and γ-Toc (Tmix, γ-Toc-rich oil) therapy was assessed against human androgen-dependent prostate cancer cells (LNCaP). We found that combined treatment of δ-T3 (10 μM) and γ-Toc (5 μM) resulted in reinforced anti-prostate cancer activity. Specifically, cell cycle phase distribution analysis revealed that in addition to G1 arrest caused by the treatment with δ-T3, the combination of δ-T3 with γ-Toc induced G2/M arrest. Enhanced induction of apoptosis by the combined treatment was also observed. These findings indicate that combination of δ-T3 and γ-Toc significantly inhibits prostate cancer cell growth due to the simultaneous cell cycle arrest in the G1 phase and G2/M phase.