- 著者
- Karin Takeda Masaya Oda Takemichi Okada Hitoshi Yamazaki Makoto Ohbu Masaaki Watanabe Hiroaki Yokomori
- 出版者
- 一般社団法人 日本内科学会
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.55, no.10, pp.1293-1297, 2016 (Released:2016-05-15)
- 参考文献数
- 12
- 被引用文献数
- 1 3
A 64-year-old man seeking treatment for a common cold was admitted to our hospital due to symptoms of general fatigue and liver dysfunction. A thorough history review revealed that the patient had recently started taking an over-the-counter (OTC) drug. Drug-induced lymphocyte stimulation tests were positive. Serum markers for autoimmune hepatitis (AIH) were particularly elevated. Liver biopsy revealed spotty necrosis and ceroid-pigmented Kupffer cells and piecemeal necrosis with multiple plasma cells. He responded to corticosteroids, thus suggesting the presence of an immune-mediated component associated with the liver injury. Liver injury after using OTCs should be included in the differential diagnosis for chronic hepatitis with features of AIH.
- 著者
- Mari KUSUMI Hidehiro OKA Hidehito KIMURA Hitoshi YAMAZAKI Koji KONDO Toshihiro KUMABE
- 出版者
- The Japan Neurosurgical Society
- 雑誌
- NMC Case Report Journal (ISSN:21884226)
- 巻号頁・発行日
- vol.9, pp.217-223, 2022-12-31 (Released:2022-07-19)
- 参考文献数
- 24
- 被引用文献数
- 1
There has been a noted increase in the incidence of intracranial aspergillosis; this is often attributed to the wider use of antibiotics, corticosteroids, and immunosuppressants. Fungal cerebral aneurysms due to aspergillosis after neurosurgery remain extremely rare; in fact, only seven cases have been reported in the literature. In this study, we present a patient with an Aspergillus aneurysm that elicited subarachnoid hemorrhage after endoscopic endonasal surgery (EES) for craniopharyngioma. A 70-year-old woman with recurrent craniopharyngioma and steroid treatment underwent uneventful EES. On the 5th postoperative day, she suffered subarachnoid hemorrhage. As per her computed tomography angiography findings, an aneurysm was detected on the left internal carotid artery (ICA). Subsequent digital subtraction angiography showed occlusion of the ICA and an irregularly shaped wall. The diagnosis was pseudoaneurysm. We then performed craniotomy to place a left high-flow bypass and to trap the pseudoaneurysm. Despite continuous intensive care, she died on the 25th postoperative day of a huge, left cerebral infarct. The final diagnosis was made at autopsy; it revealed destruction of the ICA and Aspergillus invasion of the vessel wall, confirming the presence of a true fungal aneurysm. Perioperatively, patients with potential immunosuppression must be carefully managed. Advanced age is a risk factor. As surgery via the paranasal sinuses raises the risk for aspergillosis, fungal infection must be ruled out in patients whose postoperative course is deemed concerning.
- 著者
- 小山 明 鈴木 明 藤山 哲朗 岡部 憲明 山﨑 均 大内 克哉 久冨 敏明 尹 智博 Akira KOYAMA Akira SUZUKI Tetsuro FUJIYAMA Noriaki OKABE Hitoshi YAMAZAKI Katsuya OUCHI Toshiaki HISATOMI Jibak YOON
- 出版者
- 神戸芸術工科大学
- 雑誌
- 芸術工学2013
- 巻号頁・発行日
- 2013-11-25
研究の目的は、インタラクションデザインに関するこれまでの学術的な交流や研究の基盤に立ち、日本における新しい教育領域・教育方法としてのインタラクションデザインの可能性もしくは問題点などを、実際の教育現場において確認し、導入のための基礎を構築することにある。本研究の中心となったのは、2012年12月17~21日に開催したスプツニ子!客員教授によるインタラクションデザインワークショップである。これは「Body Futures」をテーマとした、未来における身体の在り方を考えるワークショップであり、公開講評会をKIITOで行ない、提案された各グループのプロジェクトは2013年2月22~28日の期間、同じくKIITOにおいて開催された「Body Futures展」において展示された。このワークショップでは、大学院と学部の連携、大学と企業(アシックス)との連携が試みられた。異なる年齢層の参加者間の連携と、異なる組織領域間の連携が新たな発想を生み出し、「未来の身体」を様々な観点からとらえた科学的な提案が行なわれた。The objective of this study is to identify possibilities and problems related to interaction design within actual educational practice, and thus to construct a foundation for its introducation as a new field and methodology of study in Japan. The main part of this study derives from an interaction design workshop conducted 17-21 December 2012 by Visiting Professor Sputniko! (Hiromi Ozaki) entitled "Body Futures" that proposed to consider further dimensions of physicality. An open forum was subsequently held at KIITO and group projects developed from the workshop were exhibited 22-28 February 2013 under the same Body Futures title, again at KIITO. This workshop attempted to create linkages between the graduate school and university departments, as well as between the university and commercial enterprise (ASICS). It spawned connections between participants of different ages, fostered new thinking across diverse organisational sectors, and proposed various scientific ideas about the future of the body.