著者

Sayaka Hikida Shinichiro Morioka Naoki Fujii Taichi Tajima Yuriko Terayama Yuriko Sugiura Masahiro Ishikane Jin Takasaki Masayuki Hojo Norio Ohmagari

出版者

National Center for Global Health and Medicine

雑誌

Global Health & Medicine (ISSN:24349186)

巻号頁・発行日

pp.2021.01092, (Released:2021-08-10)

参考文献数

8

被引用文献数

2

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We investigated possible sources of newly infected patients with coronavirus disease (COVID-19) after the fourth wave in order to explore unknown sources. Retrospective chart review on all the confirmed patients with COVID-19 admitted to the National Center for Global Health and Medicine (NCGM) in Tokyo, Japan was conducted from May 22 through June 29, 2021. Among the 22 participants, 14 (64%) had a history of known high-risk infection behaviors. Of those, 12 reported that their activities involved eating and drinking. In addition, there were 24 high-risk situations, of those, 21 (88%) were related to indoor dining, and masks were not worn in 22 situations (92%). New source of infection has not been identified. In situations with a high known risk of infection, many cases were related to eating and drinking, and insufficient use of masks was evident. Raising risk awareness on infection prevention and control of COVID-19 is urgently needed.

著者

Keiji Nakamura Satoshi Ide Sho Saito Noriko Kinoshita Satoshi Kutsuna Yuki Moriyama Tetsuya Suzuki Masayuki Ota Hidetoshi Nomoto Tetsuya Mizoue Masayuki Hojo Jin Takasaki Yusuke Asai Mari Terada Yutaro Akiyama Yusuke Miyazato Takato Nakamoto Yuji Wakimoto Mugen Ujiie Kei Yamamoto Masahiro Ishikane Shinichiro Morioka Kayoko Hayakawa Haruhito Sugiyama Norio Ohmagari

出版者

National Center for Global Health and Medicine

雑誌

Global Health & Medicine (ISSN:24349186)

巻号頁・発行日

vol.2, no.3, pp.174-177, 2020-06-30 (Released:2020-07-04)

参考文献数

8

被引用文献数

7

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Since the initial report of coronavirus disease (COVID-19) from the City of Wuhan, China in December 2019, there have been multiple cases globally. Reported here are 11 cases of COVID-19 at this hospital; all of the patients in question presented with relative bradycardia. The severity of the disease was classified into four grades. Of the patients studied, 3 with mild COVID-19 and 3 with moderate COVID-19 improved spontaneously. Lopinavir/ritonavir was administered to 3 patients with severe COVID-19 and 2 with critical COVID-19. Both patients with critical COVID-19 required mechanical ventilation and extracorporeal membrane oxygenation. Both patients with critical COVID-19 had a higher fever that persisted for longer than patients with milder COVID-19. The respiratory status of patients with critical COVID-19 worsened rapidly 7 days after the onset of symptoms. Relative bradycardia may be useful in distinguishing between COVID-19 and bacterial community-acquired pneumonia. In patients who have had a fever for > 7 days, the condition might worsen suddenly.

著者

Kayoko Hayakawa Satoshi Kutsuna Takeo Kawamata Yuko Sugiki Chiharu Nonaka Keiko Tanaka Michi Shoji Masaki Nagai Shunsuke Tezuka Kazuyuki Shinya Hiroki Saito Takahiro Harada Nin Moriya Motoyuki Tsuboi Masataro Norizuki Yasuo Sugiura Yasuyo Osanai Masaya Sugiyama Ayako Okuhama Kohei Kanda Yuji Wakimoto Mugen Ujiie Shinichiro Morioka Kei Yamamoto Noriko Kinoshita Masahiro Ishikane Sho Saito Yuki Moriyama Masayuki Ota Keiji Nakamura Takato Nakamoto Satoshi Ide Hidetoshi Nomoto Yutaro Akiyama Tetsuya Suzuki Yusuke Miyazato Yoshiaki Gu Nobuaki Matsunaga Shinya Tsuzuki Yumiko Fujitomo Yoshiki Kusama Hiroyuki Shichino Masao Kaneshige Junko Yamanaka Miki Saito Masayuki Hojo Masao Hashimoto Shinyu Izumi Jin Takasaki Manabu Suzuki Keita Sakamoto Yukio Hiroi Sakurako Emoto Makoto Tokuhara Toshiaki Kobayashi Koichiro Tomiyama Fumihiko Nakamura Norio Ohmagari Haruhito Sugiyama

出版者

National Center for Global Health and Medicine

雑誌

Global Health & Medicine (ISSN:24349186)

巻号頁・発行日

vol.2, no.2, pp.107-111, 2020-04-30 (Released:2020-05-10)

参考文献数

11

被引用文献数

25

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Due to the significant spread of a new type of coronavirus (SARS-CoV-2) infection (COVID-19) in China, the Chinese government blockaded several cities in Hubei Province. Japanese citizens lost a means of transportation to return back to Japan. The National Center for Global Health and Medicine (NCGM) helped the operation of charter flights for evacuation of Japanese residents from Hubei Province, and this article outlines our experiences. A total of five charter flights were dispatched, and the majority of returnees (793/829 [95.7%]) were handled at NCGM. A large number of personnel from various departments participated in this operation; 107 physicians, 115 nurses, 110 clerical staff, and 45 laboratory technicians in total. Several medical translators were also involved. In this operation, we conducted airborne precautions in addition to contact precautions. Eye shields were also used. The doctors collecting the pharyngeal swab used a coverall to minimize the risk of body surface contamination from secretions and droplets. Enhanced hand hygiene using alcohol hand sanitizer was performed. Forty-eight persons were ultimately hospitalized after the triage at NCGM operation, which was more than the number of persons triaged at the airport (n = 34). Of those hospitalized after NCGM triage, 8.3% (4/48 patients) ultimately tested positive for SARS-CoV-2, significantly higher than the positive rate among subjects not triaged (4/48 [8.3%] vs. 9/745 [1.2%]: p = 0.0057). NCGM participated in a large-scale operation to evacuate Japanese nationals from the COVID-19 epidemic area. We were able to establish a scheme through this experience that can be used in the future.

著者

Shion Miyoshi Jin Takasaki Sohtaro Mine Masanori Kono Toru Igari Yuichiro Takeda Masayuki Hojo Haruhito Sugiyama

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.56, no.9, pp.1079-1083, 2017-05-01 (Released:2017-05-01)

参考文献数

16

被引用文献数

3

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Anti-tumor necrosis factor α (anti-TNFα) agents increase the risk of tuberculosis (TB), but cases are rarely fatal. This report concerns a patient who was undergoing treatment with infliximab and presented with acute respiratory distress syndrome due to miliary TB without a miliary shadow. The findings of a pathological autopsy revealed innumerable granulomas in the organs, and the miliary nodules in the lung consisted of more unstructured granulomas. Anti-TNFα agents are unusual in the presentation of TB. It is important, particularly for patients receiving anti-TNFα agents, to constantly consider the possibility of TB and to prepare for appropriate management.

著者

Kayoko Hayakawa Satoshi Kutsuna Takeo Kawamata Yuko Sugiki Chiharu Nonaka Keiko Tanaka Michi Shoji Masaki Nagai Shunsuke Tezuka Kazuyuki Shinya Hiroki Saito Takahiro Harada Nin Moriya Motoyuki Tsuboi Masataro Norizuki Yasuo Sugiura Yasuyo Osanai Masaya Sugiyama Ayako Okuhama Kohei Kanda Yuji Wakimoto Mugen Ujiie Shinichiro Morioka Kei Yamamoto Noriko Kinoshita Masahiro Ishikane Sho Saito Yuki Moriyama Masayuki Ota Keiji Nakamura Takato Nakamoto Satoshi Ide Hidetoshi Nomoto Yutaro Akiyama Tetsuya Suzuki Yusuke Miyazato Yoshiaki Gu Nobuaki Matsunaga Shinya Tsuzuki Yumiko Fujitomo Yoshiki Kusama Hiroyuki Shichino Masao Kaneshige Junko Yamanaka Miki Saito Masayuki Hojo Masao Hashimoto Shinyu Izumi Jin Takasaki Manabu Suzuki Keita Sakamoto Yukio Hiroi Sakurako Emoto Makoto Tokuhara Toshiaki Kobayashi Koichiro Tomiyama Fumihiko Nakamura Norio Ohmagari Haruhito Sugiyama

出版者

National Center for Global Health and Medicine

雑誌

Global Health & Medicine (ISSN:24349186)

巻号頁・発行日

pp.2020.01036, (Released:2020-04-29)

参考文献数

11

被引用文献数

25

---

Due to the significant spread of a new type of coronavirus (SARS-CoV-2) infection (COVID-19) in China, the Chinese government blockaded several cities in Hubei Province. Japanese citizens lost a means of transportation to return back to Japan. The National Center for Global Health and Medicine (NCGM) helped the operation of charter flights for evacuation of Japanese residents from Hubei Province, and this article outlines our experiences. A total of five charter flights were dispatched, and the majority of returnees (793/829 [95.7%]) were handled at NCGM. A large number of personnel from various departments participated in this operation; 107 physicians, 115 nurses, 110 clerical staff, and 45 laboratory technicians in total. Several medical translators were also involved. In this operation, we conducted airborne precautions in addition to contact precautions. Eye shields were also used. The doctors collecting the pharyngeal swab used a coverall to minimize the risk of body surface contamination from secretions and droplets. Enhanced hand hygiene using alcohol hand sanitizer was performed. Forty-eight persons were ultimately hospitalized after the triage at NCGM operation, which was more than the number of persons triaged at the airport (n = 34). Of those hospitalized after NCGM triage, 8.3% (4/48 patients) ultimately tested positive for SARS-CoV-2, significantly higher than the positive rate among subjects not triaged (4/48 [8.3%] vs. 9/745 [1.2%]: p = 0.0057). NCGM participated in a large-scale operation to evacuate Japanese nationals from the COVID-19 epidemic area. We were able to establish a scheme through this experience that can be used in the future.

著者

Ryutaro Tanizaki Jin Takasaki

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.53, no.13, pp.1457-1458, 2014 (Released:2014-07-01)

参考文献数

2