著者
Liang Fu Yong Feng Tantan Ren Min Yang Qianting Yang Yi Lin Hui Zeng Jiaohong Zhang Lei Liu Qingyun Li Mengqi He Peize Zhang Haibin Chen Guofang Deng
出版者
International Research and Cooperation Association for Bio & Socio-Sciences Advancement
雑誌
BioScience Trends (ISSN:18817815)
巻号頁・発行日
pp.2022.01476, (Released:2023-01-02)
参考文献数
19
被引用文献数
2

Mycobacterium tuberculosis (M.tb) infects a quarter of the world's population and may progress to active tuberculosis (ATB). There is no gold standard for diagnosing latent tuberculosis infection (LTBI). Some immunodiagnostic tests are recommended to detect LTBI but can not distinguish ATB from LTBI. The breath test is useful for diagnosing ATB compared to healthy subjects but was never studied for LTBI. This proof-of-concept study (Chinese Clinical Trials Registry number: ChiCTR2200058346) was the first to explore a novel, rapid, and simple LTBI detection method via breath test on high-pressure photon ionization time-of-flight mass spectrometry (HPPI-TOFMS). The case group of LTBI subjects (n = 185) and the control group (n = 250), which included ATB subgroup (n = 121) and healthy control (HC) subgroup (n = 129), were enrolled. The LTBI detection model indicated that a breath test via HPPI-TOFMS could distinguish LTBI from the control with a sensitivity of 80.0% (95% CI: 67.6%, 92.4%) and a specificity of 80.8% (95% CI: 71.8%, 89.9%). Nevertheless, further intensive studies with a larger sample size are required for clinical application.
著者
Mei-Yin Chien Chih-Min Yang Chao-Hsiang Chen
出版者
Pesticide Science Society of Japan
雑誌
Journal of Pesticide Science (ISSN:1348589X)
巻号頁・発行日
vol.47, no.1, pp.30-34, 2022-02-20 (Released:2022-02-20)
参考文献数
12
被引用文献数
10

Over ten-year routine inspection results on organochlorine pesticide (OCP) residue were summarized, OCPs residues, including BHC isomers (α, β, γ, and δ-BHC), DDT analogs (p,p′-DDD, p,p′-DDE, o,p′-DDT, and p,p′-DDT), and pentachloronitrobenzene (PCNB) and its metabolites (pentachloroaniline and methyl pentachlorophenyl sulfide (MPCPS)), in 1,665 samples for 37 types of Chinese herbal medicine (CHM) using the QuEChERS method coupled with the GC-ECD. Based on the maximal residue levels for OCPs set by Asian pharmacopeias, PCNB contamination in Ginseng radix as well as the total DDT and PCNB contamination in Panacis quinquefolii radix are of concern. OCP residues in different parts of Panax ginseng were also compared. The total BHC residue in leaf and fibrous root, as well as the total DDT and PCNB residue in all parts, exceeded MRL of 0.1 mg/kg. Overall, this study provided meaningful results about OCP residue in CHM for pharmaceutical industries and consumers.
著者
Wei-Ping Huang Chun-Hung Chen Yong-Chih Chou Dong-Yih Lin Sheng-Min Yang
出版者
(公社)日本金属学会/(一社)軽金属学会,(一社)資源・素材学会,ナノ学会,(公社)日本金属学会,(一社)日本塑性加工学会,(公社)日本鋳造工学会,日本銅学会,(一社)日本熱処理技術協会,(一社)日本熱電学会,(一社)日本非破壊検査協会,(一社)日本溶射学会,(一社)粉体粉末冶金協会,(公社)腐食防食学会
雑誌
MATERIALS TRANSACTIONS (ISSN:13459678)
巻号頁・発行日
vol.54, no.4, pp.553-560, 2013-04-01 (Released:2013-03-25)
参考文献数
16
被引用文献数
1

Silver-containing 2205 duplex stainless steel was developed to study its phase transformation, precipitating behavior, as well as corrosion resistance. The result reveals that the doping of silver in 2205 duplex stainless steel decreased the γ2 phase volume fraction. In addition, the solubility of silver in iron was extremely low, and silver particles were distributed randomly both in the matrix and on the boundaries of the material. Silver particles were observed on the material surface and the number of particles on the surface increased with the silver content.The pitting corrosion resistance of the test materials decreased with increasing silver content. The pits on the material surface became more abundant when the silver content was increased. The protective function of continuous Cr2O3 film on the surface of the steel was destroyed by the silver particles that weakened the pitting resistance. In addition, the initiation of pitting corrosion usually occurred around the γ2 phase, which had low concentrations of chromium and molybdenum.