- 著者
- Weina Gao Jianquan Wu Jingyu Wei Lingling Pu Changjiang Guo Jijun Yang Ming Yang Haiji Luo
- 出版者
- SOCIETY FOR FREE RADICAL RESEARCH JAPAN
- 雑誌
- Journal of Clinical Biochemistry and Nutrition (ISSN:09120009)
- 巻号頁・発行日
- vol.55, no.1, pp.7-10, 2014 (Released:2014-07-01)
- 参考文献数
- 48
- 被引用文献数
- 15 45
Aging weakened innate and adaptive immunity both quantitatively and qualitatively. Some components in propolis could stimulate immune function in young animals or cultured immune cells in vitro. Few studies had been carried out in the aged. The present study was to evaluate the effects of Brazilian green propolis supplementation on the immunological parameters in aged mice. Eighty Kunming mice, aged 15–18 months, were randomly assigned to the control and three experimental groups supplemented with different doses (83.3, 157.4 and 352.9 mg/kg.bw respectively) of Brazilian green propolis. The experiment lasted for 4 weeks. Contents of total polyphenol, flavonoid, cinnamic acid and artepillin-C in Brazilian green propolis were analyzed. Splenic NK cytotoxic, T lymphocyte proliferation and antibody generation cells, as well as the phagocytosis of peritoneal macrophages, ear swelling, and serum contents of IgG, IgM, hemolysin and cytokines were measured. After 4 weeks of treatment, the phagocytosis of peritoneal macrophages was enhanced in 157.4 mg/kg and 352.9 mg/kg groups. Ear swelling increased in all propolis treatmented groups. Antibodies specific to sheep erythrocytes were higher in the groups receiving 157.4 and 352.9 mg/kg.bw than that of control group. IgG level dramatically increased in the groups receiving 83.3 and 157.4 mg/kg.bw in comparison to the control group. These results indicate that administration of Brazilian green propolis have a positive effect on innate and adaptive immunity in aged mice.
- 著者
- Ming YANG Masafumi HAGIWARA
- 出版者
- Japan Society of Kansei Engineering
- 雑誌
- International Journal of Affective Engineering (ISSN:21875413)
- 巻号頁・発行日
- vol.15, no.2, pp.125-134, 2016 (Released:2016-06-30)
- 参考文献数
- 29
- 被引用文献数
- 1
In this paper, we propose an automatic Waka generation system with custom database, based on texts given by the user. The proposed text-based system has better compatibility with Waka poem, improving consistence and logicality of generated poems. Kansei information is also considered to make poems natural and closer to the emotions the user wants to express. Presented by interactive generation experiments, the proposed system can generate Waka poems reflecting stylistic and grammatical requirements. Meanwhile, the poems are also with related meanings and emotions to the original text and some poeticness.