著者

Atsushi Hiraga Takeshi Yamaoka Yukari Sakai Yoshihiro Osakabe Aki Suzuki Noboru Hirose

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.30, no.10, pp.1310-1314, 2018 (Released:2018-10-12)

参考文献数

16

被引用文献数

5

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[Purpose] The purpose of this study is to examine the effectiveness of a stroke-related scale with regard to outcome, onset, and timing of stroke patients. [Participants and Methods] The participants included 583 out of 996 patients who were admitted to the stroke care unit.The outcomes and 3 stroke scale (National Institutes of Health Stroke Scale: NIHSS, Functional Independence Measure: FIM, modified Rankin Scale: mRS) scores immediately at hospitalization, on day 7 after onset, and on day 30 after onset were investigated. This study was analyzed using a generalization linear model with a binomial distribution. The comparisons between outcomes were made in terms of home discharge versus convalescence, and convalescence versus hospital transfer. [Results] Comparisons of home discharge versus convalescence hospital transfer showed a significant difference in the NIHSS and mRS scores at the time of hospitalization, and a significant difference in the NIHSS scale score on day 7 after onset. In comparisons between convalescence and hospital transfer, significant differences were observed in NIHSS and FIM scores at hospitalization, and the FIM scale score showed significant differences on day 7 and day 30. [Conclusion] The study suggested the efficacy of using multiple scales for prediction of stroke outcome with higher accuracy.

著者

Eri Ohto-Fujita Nozomi Hatakeyama Aya Atomi Shunsuke Yasuda Shoki Kodama Tomoaki Atomi Kazuya Tanaka Noboru Hirose Kenji Harada Yoshihide Asano Toshiyuki Watanabe Yukio Hasebe Miho Shimizu Yoriko Atomi

出版者

The Society of Fiber Science and Technology, Japan

雑誌

Journal of Fiber Science and Technology (ISSN:21897654)

巻号頁・発行日

vol.77, no.10, pp.258-265, 2021 (Released:2021-10-23)

参考文献数

49

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Chicken eggshell membrane (ESM) is a two-layered insoluble sheet located between the eggshell and the albumen and is composed of fibrous proteins. Naturally occurring composite material, such as ESM have various ameliorative effects for osteoarthritis of the knee, joint, and connective tissue when ingested and absorbed as supplements. The physiological effects by oral ESM intake, especially on respiratory function,remain unclear. We have recently reported that tritium-labeled ESM powder can be digested and absorbed by mice and distributed in tissues throughout the body. We have also reported that the application of hydrolyzed water-soluble ESM to human skin significantly improved skin elasticity, which declines with aging, in a before and after comparison at 3 months, and significantly reduced wrinkles at the corners of the eyes compared to controls. In the present double-blind, placebo-controlled study, we examined breathing, skin, and body functions, such as zigzag walking, after ESM ingestion compared to controls. We hypothesized this to improve physical functions by improving the extracellular matrix (ECM) within the range of homeostasis. Among 20 healthy subjects (age: 21–68 years), the group given ESM supplementation for 8 weeks showed significantly increased rate of change in arm skin elasticity, respiratory function (forced expiratory volume in 1 s to forced vital capacity ratio (FEV1/FVC)), and zigzag walking speed compared to controls. There was a significant correlation between the rate of change in FEV1/FVC and that of zigzag walking after 8 weeks compared to the initial values. These functional improvements observed in skin elasticity, lung function, and motor function with oral intake of ESM suggest that maintaining elasticity in the cellular environment can support overall health and activity levels.

著者

Wakana Katsuta Masahiro Aihara Noboru Hirose Fumiaki Saito Hiroki Hagiwara

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.30, no.1, pp.42-46, 2018 (Released:2018-01-27)

参考文献数

16

被引用文献数

1

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[Purpose] Changes in oxidative stress severity and antioxidant potential are routinely used as oxidative stress markers. While several studies have reported the relationship between these markers and exercise, little is known about the dynamic nature of these markers during muscle atrophy and reloading. Therefore, we examined changes in oxidative stress severity and antioxidant potential during muscle atrophy and reloading. [Subjects and Methods] Muscle atrophy was induced in mice by casting the limb for 2 weeks. Mice were then subjected to reloading for 2 weeks. The severity of oxidative stress (hydroperoxide) and antioxidant potential (degree of reduction) were quantified. [Results] Muscle atrophy was induced by cast immobilization. The muscle mass of mice recovered to similar levels as the control group following 2 weeks of reloading. The degree of oxidative stress was within the normal range throughout the experimental period. The antioxidant potential decreased to the clinical borderline level 2 weeks after immobilization, further decreased after 1 day of reloading, and then recovered to within the normal range. [Conclusion] Performing d-ROMs and BAP tests may contribute to the understanding to atrophic process of skeletal muscle in clinical practice of physical therapy.