- 著者
- Jeong Hui Kim Ryosuke Kikuchi Atsuo Suzuki Rika Watarai Kaori Goto Yui Okumura Tadashi Matsushita
- 出版者
- Japanese Society of Laboratory Medicine
- 雑誌
- Laboratory Medicine International (ISSN:24368660)
- 巻号頁・発行日
- vol.2, no.3, pp.60-66, 2023 (Released:2023-12-29)
- 参考文献数
- 24
The immune system produces antibodies following SARS-CoV-2 infection and vaccination. However, we lack comprehensive information about the humoral responses after infection and vaccination, which are similar but might differ in type or amount of produced antibodies. Therefore, we compared different types and amounts of antibodies produced by the immune system in response to infection versus those produced by BNT162b2 (Pfizer/BioNTech) vaccines. Our findings indicated that naturally infected individuals had 14-fold higher anti-SARS-CoV-2 spike protein (anti-S) and 41-fold higher anti-SARS-CoV-2 receptor-binding domain of the viral spike protein (anti-RBD) IgM titers than SARS-CoV-2-naïve vaccinees. Remarkably, naturally infected individuals maintained high levels of IgM antibody titers up to six weeks after symptom onset. A significantly rapid increase in anti-S IgG titers in primary infection was observed, eventually reaching a level similar to that in people who had third booster vaccination. This study revealed the characteristics of the target antigen and immunoglobulin isotypes after natural SARS-CoV-2 infection and COVID-19 vaccination.
- 著者
- Satoko MOTAI Hiroki MUKAI Tetsu WATANUKI Kenji OHWADA Tatsuo FUKUDA Akihiko MACHIDA Chisaki KURAMATA Ryosuke KIKUCHI Tsuyoshi YAITA Toshihiro KOGURE
- 出版者
- 一般社団法人日本鉱物科学会
- 雑誌
- Journal of Mineralogical and Petrological Sciences (ISSN:13456296)
- 巻号頁・発行日
- pp.150722, (Released:2016-06-08)
- 被引用文献数
- 15
Radioactive particles of around 50 µm size were collected from highly contaminated soil in the Fukushima Prefecture, Japan, and characterized using micro X–ray diffraction with synchrotron radiation (SR–µ–XRD). Two–dimensional diffraction patterns from individual particles rotated during X–ray irradiation were recorded on a flat imaging plate and a one–dimensional diffraction profile, as a function of 2θ, was derived from the pattern. Weathered biotite (WB) particles with plate–like morphology showed a broad peak corresponding to a basal reflection with d = 10–14 Å, indicating various degrees of vermiculitization. Another peak of ∼ 7 Å was also detected in these WB particles, suggesting the parallel growth of kaolinite in the biotite particles. These characteristics were also found in the WB collected from an Abukuma granitic body, which is widespread in the eastern part of Fukushima. SR–µ–XRD of radioactive soil particles consisting of fine minerals or of those rich in organic matter indicated that these particles contain very fine 2:1 type clay minerals alongside detrital rock–forming minerals such as quartz and feldspar.