- 著者
- Tomoko Tajiri Chisako Wada Hirotsugu Ohkubo Norihisa Takeda Kensuke Fukumitsu Satoshi Fukuda Yoshihiro Kanemitsu Takehiro Uemura Masaya Takemura Ken Maeno Yutaka Ito Tetsuya Oguri Akio Niimi
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- pp.4746-20, (Released:2020-07-21)
- 参考文献数
- 17
- 被引用文献数
- 12
Acute eosinophilic pneumonia (AEP) is an acute respiratory illness with diffuse pulmonary infiltrates and pulmonary eosinophilia. While the etiology of AEP remains unclear, a relationship between cigarette smoking and AEP onset has been suggested. The use of heated tobacco products (HTPs) has been growing, but the impact of these products on our health is not fully understood. We herein report a case of AEP that developed after switching from conventional cigarette to HTP smoking. The patient's condition improved after the cessation of HTP smoking and corticosteroid treatment initiation. In cases of AEP, physicians should consider HTPs use as a possible cause.
- 著者
- Yuya Hagiwara Yoshiyuki Yamamoto Yuki Inagaki Reina Tomisaki Miki Tsuji Soma Fukuda Satoshi Fukuda Tsubasa Onoda Hirosumi Suzuki Yusuke Niisato Yoshitaka Tange Naoya Ikeda Keiichi Yamada Mariko Kobayashi Daisuke Akutsu Takeshi Yamada Toshikazu Moriwaki Toshiaki Narasaka Hideo Suzuki Kiichiro Tsuchiya
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.61, no.16, pp.2449-2455, 2022-08-15 (Released:2022-08-15)
- 参考文献数
- 43
- 被引用文献数
- 1
Dihydropyrimidine dehydrogenase (DPD) deficiency induces severe adverse events in patients receiving fluoropyrimidines. We encountered a 64-year-old DPD-deficient man with a severe capecitabine-related gastrointestinal disorder. He received capecitabine-containing chemotherapy after rectal cancer resection. During the first course of chemotherapy, he developed severe diarrhea, a fever, and hematochezia. Endoscopy revealed mucosal shedding with bleeding throughout the gastrointestinal tract. DPD deficiency was suspected because he developed many severe adverse events of capecitabine early and was finally confirmed based on the finding of a low DPD activity level in peripheral blood mononuclear cells. After one month of intensive care, hemostasis and mucosal healing were noted, although his gastrointestinal function did not improve, and he had persistent nutritional management issues.
- 著者
- Toshihiko Hayashi Ryusuke Kyan Satoshi Fukuda Kouji Mizota
- 出版者
- 公益社団法人 日本理学療法士協会
- 雑誌
- 理学療法学Supplement Vol.44 Suppl. No.2 (第52回日本理学療法学術大会 抄録集)
- 巻号頁・発行日
- pp.1682, 2017 (Released:2017-04-24)
【Purpose】In the clinical training of the physical therapist(following, PT), it lasts for a case report and a daily notebook, many divergences including the investigation learning that are imposed during training, and were demanded, and the burden was big quantitatively in terms of time. We tried to clarify this fact by objective data handling.【Methods】We explained this action beforehand and intended for the leader of training 5 facilities where the agreement was provided and the person in charge, nine trainee and three teachers of our academy. And we visited each facility once a week for the hearing of students and RPT. We performed analysis using the technique called“text mining”in this report in order to evade risk as much as possible.Soft“KH Coder”which I used this time abolishes“the manual labor”that can become arbitrary on choosing the word, and operation enables freedom in making it and coexistence of the objectivity by stepping on a procedure to show summarizing the whole data by a multivariate analysis, and showing it and a coding rule.【Results】As a result, the positive item showed a tendency to become higher in the middle stage of clinical training. And negative became decreased after the fourth week. In addition, as a result of co-occurrence network by the text mining, each comments of progress note tended to change every week.【Discussion】As a result of co-occurrence network from a progressive notebook, the data said that teacher's intervention were necessary that adaptation to the environment of the student and support about the on-site learning.