著者
Masayuki Konishi Masaki Takahashi Naoya Endo Shigeharu Numao Shun Takagi Masashi Miyashita Taishi Midorikawa Katsuhiko Suzuki Shizuo Sakamoto
出版者
一般社団法人日本体力医学会
雑誌
The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日
vol.2, no.1, pp.121-126, 2013-03-25 (Released:2013-04-08)
参考文献数
31
被引用文献数
1 2

The aim of this study was to investigate the effects of one night of sleep deprivation on maximal fat oxidation during a graded exercise test. Ten healthy young males underwent two 2-day control and sleep deprivation trials. Participants were allowed normal sleep from 2300 to 0700 for the control trial, whereas they were required to stay awake for 34 h during the sleep deprivation trial. At 1700 on day 2, participants performed a graded exercise test to exhaustion on a treadmill; this allowed us to determine maximal oxygen uptake and maximal fat oxidation. Before and immediately after the graded exercise test, blood samples were collected in order to measure glucose, insulin, free fatty acid, and triglyceride concentrations. Plasma glucose concentrations were significantly higher in the sleep deprivation trial than in the control trial before the graded exercise test. Serum insulin and free fatty acid concentrations were not significantly different between the two trials. Serum triglyceride concentrations were significantly lower in the sleep deprivation trial than in the control trial. The maximal fat oxidation rate, oxygen uptake, and heart rate at maximal fat oxidation intensity, during the graded exercise test, were not significantly different between the two trials. These findings suggest that maximal fat oxidation during graded exercise is unaffected by one night of sleep deprivation.
著者
Masaki Takahashi Katsuhiko Suzuki Hideki Matoba Shizuo Sakamoto Shigeru Obara
出版者
一般社団法人日本体力医学会
雑誌
The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日
vol.1, no.1, pp.183-189, 2012-05-25 (Released:2012-08-22)
参考文献数
36
被引用文献数
2 7

The purpose of this study was to investigate the effects of three different intensities of exercise on oxidative stress and antioxidant capacity. Eight healthy male subjects performed three different intensities of exercise for 20 minutes: (1) 70% anaerobic threshold (AT) (light intensity, LI), (2) 100% AT (moderate intensity, MI), and (3) 130% AT (high intensity, HI) on a cycle ergometer. A control (C) trial was conducted under resting conditions. Blood samples were taken pre-exercise, immediately and 30 min after exercise. In the HI trial only, the concentrations of plasma derivatives of reactive oxygen metabolites (d-ROMs) were significantly higher immediately (P<0.01) and 30 min after exercise (P<0.05) than at pre-exercise. Furthermore, plasma trolox equivalent antioxidant capacity was significantly higher immediately after exercise in the HI trial (P<0.01). And, plasma glutathione peroxidase (GPX) activity was significantly higher immediately after exercise than at pre-exercise in the MI (P<0.05) and HI trials (P<0.01). These data suggest that 20 min of pedaling exercise above the AT level may increase ROS production, while endogenous enzyme activity (especially GPX activity) or non-enzymatic antioxidants may modulate exercise-induced ROS generation. Thus, exercise under the AT level induces very little oxidative stress damage in young people.
著者
Hiroki TABATA Hyeon-ki KIM Masayuki KONISHI Naoya ENDO Shizuo SAKAMOTO
出版者
Japanese Society of Clinical Physiology
雑誌
日本臨床生理学会雑誌 (ISSN:02867052)
巻号頁・発行日
vol.49, no.5, pp.191-200, 2019-12-01 (Released:2020-03-06)
参考文献数
40

Objectives: This study aimed to investigate the substrate metabolism response to moderateand high-intensity equicaloric exercises in endurance-trained men. Methods: Ten male endurance-trained runners (mean ± standard error: age, 22 ± 1 years; body mass index, 19.3 ± 0.7 kg/m2; ⩒O2max, 64.1 ± 2.1 mL/kg/min) performed a graded exercise test on a treadmill to determine the exercise intensity at which elicits maximal fat oxidation (Fatmax) and subsequently completed two equicaloric exercises (53 min at Fatmax and 30 min at 65%⩒O2max). Substrate oxidation rates during exercise and 2-h post-exercise recovery period were determined using indirect calorimetry. Blood samples were collected before exercise; immediately post-exercise; and at 30 min, 1 h, and 2 h post-exercise to determine plasma noradrenaline, serum growth hormone (GH), and free fatty acid (FFA) concentrations. Results: Mean Fatmax was observed at 37.3 ± 4.6 %⩒O2max. Fat oxidation volume during exercise was significantly higher in the Fatmax trial than in the 65%⩒O2max trial (15.2 ± 1.5 g vs 8.5 ± 0.7 g, P < 0.01). No significant difference in fat oxidation occurred in the post-exercise recovery period. Serum GH and plasma noradrenaline concentrations were higher at 65%⩒O2max than at Fatmax immediately post-exercise (P < 0.05). However, there was no difference in serum FFA levels between exercise intensities. Conclusions: Exercise at Fatmax oxidized more fat than exercise at 65%⩒O2max when matched for energy expenditure during exercise in endurance-trained men.
著者
Shizuo Sakamoto Masayuki Konishi Hyeon Ki Kim Naoya Endoh Masaki Takahashi Syun Takagi Taishi Midorikawa
出版者
一般社団法人日本体力医学会
雑誌
The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日
vol.1, no.3, pp.499-504, 2012-09-25 (Released:2012-10-23)
参考文献数
17

There have been several reports on exercise prescriptions and the effects of exercise on various diseases, particularly for fat metabolism disorder. In recent years, notably from the latter half of the 1990s, studies on effective exercise prescriptions for fat metabolism disorder have taken into account the type of exercise content (type, intensity and duration per session) that has beneficial effects on fat metabolism disorder and the post-exercise recovery period. These studies have analysed the fat oxidation rate as a parameter for examining the beneficial effects of exercise on fat metabolism disorder. In this review, studies, undertaken in Japan and overseas, are introduced that are related to exercise and the fat oxidation rate.