著者

Shan Yun Risa Takashima Mari Sakaue Daisuke Sawamura Takao Inoue Shinya Sakai

出版者

社団法人 日本作業療法士協会

雑誌

Asian Journal of Occupational Therapy (ISSN:13473476)

巻号頁・発行日

vol.19, no.1, pp.8-15, 2023 (Released:2023-02-17)

参考文献数

48

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Background: Occupational dysfunction (OD) can become a major health problem for community-dwelling older adults. OD can be experienced by older adults despite the absence of an apparent medical diagnosis or disability. Therefore, OD may be a new health indicator in the field of preventive medicine. Objectives: This study investigated possible predictors of OD in community-dwelling older adults. Methods: Fifty-four participants (aged 63-94) in Japan completed a demographic questionnaire, the Classification and Assessment of Occupational Dysfunction Scale (CAOD), assessments of functional health (Five Times Sit-to-Stand Test, Timed Up & Go, Automatic Thoughts Questionnaire-Revised, and Japan Science and Technology Agency Index of Competence), and responded about their subjective health (self-rated health). Only seven participants were men; therefore, male data were excluded from the analysis. Independent t-test and analysis of multiple regression model was performed to identify the predictors of OD. Results: The results of the independent samples t-test shows that the OD group correlated to a significant younger age, more negative automatic thoughts, and better social engagement in older women. The results of the multiple regression analysis showed that negative automatic thoughts was a significant predictor of OD among older women. Conclusion: Negatively evaluating stressful events related to occupational engagement may be associated with OD. It may be useful to assess, maintain, and improve negative automatic thoughts to prevent OD. The results of this study can provide an assessment perspective and intervention strategy focusing on occupations to occupational therapists active in the field of preventive occupational therapy.

著者

MASASHI UEMA KENZO YONEMITSU YOSHIKA MOMOSE YOSHIKAZU ISHII KAZUHIRO TATEDA TAKAO INOUE HIROSHI ASAKURA

出版者

The Society for Antibacterial and Antifungal Agents, Japan

雑誌

Biocontrol Science (ISSN:13424815)

巻号頁・発行日

vol.26, no.2, pp.119-125, 2021 (Released:2021-06-04)

参考文献数

19

被引用文献数

8

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There is a worldwide attempt to develop prevention strategies against SARS-CoV-2 transmission. Here we examined the effectiveness of tungsten trioxide (WO3)-based visible light-responsive photocatalyst on the inactivation of SARS-CoV-2 under different temperatures and exposure durations. The viral titer on the photocatalyst-coated glass slides decreased from 5.93 ± 0.38 logTCID50 /mL to 3.05 ±. 25 logTCID50/mL after exposure to 3,000 lux of the visible light irradiation for 6h at 20℃. On the other hand, lighting without the photocatalyst, or the photocatalyst-coat without lighting retained viral stability. Immunoblotting and electron microscopic analyses showed the reduced amounts of spike protein on the viral surface after the photocatalyst treatment. Our data suggest a possible implication of the photocatalyst on the decontamination of SARS-CoV-2 in indoor environments, thereby preventing indirect viral spread.

著者

Yeting HE Takao INOUE Sadahiro NOMURA Yuichi MARUTA Hiroyuki KIDA Toshitaka YAMAKAWA Yuya HIRAYAMA Hirochika IMOTO Michiyasu SUZUKI

出版者

The Japan Neurosurgical Society

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

pp.oa.2018-0112, (Released:2019-03-20)

参考文献数

29

被引用文献数

5

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Local brain cooling of an epileptic focus at 15°C reduces the number of spikes on an electrocorticogram (ECoG), terminates seizures, and maintains neurological functions. In this study, we attempted to suppress generalized motor seizures (GMSs) by cooling a unilateral sensorimotor area. GMSs were induced in rats by intraperitoneal injection of bicuculline methiodide, an antagonist of gamma-aminobutyric acid. While monitoring the ECoG and behavior, the right sensorimotor cortex was cooled for 10 min using an implanted device. The number of spikes recorded from the cooled cortex significantly decreased to 71.2% and 62.5% compared with the control group at temperatures of 15 and 5°C (both P <0.01), respectively. The number of spikes recorded from the contralateral mirror cortex reduced to 61.7% and 62.7% (both P <0.05), respectively. The ECoG power also declined to 85% and 50% in the cooled cortex, and to 94% and 49% in the mirror cortex by the cooling at 15 and 5°C, respectively. The spikes regained in the middle of the cooling period at 15°C and in the late period at 5°C. Seizure-free durations during the 10-min periods of cooling at 15 and 5°C lasted for 4.1 ± 2.2 and 5.9 ± 1.1 min, respectively. Although temperature-dependent seizure alleviation was observed, the effect of local cortical cooling on GMSs was limited compared with the effect of local cooling of the epileptic focus on GSMs.