著者
Fu-Qiang Liu Sheng-Qiang Liu Yong Zhang Yang Wang Chao Chu Dan Wang Shuo Pan Jun-Kui Wang Qi Yu Jian-Jun Mu
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-16-0756, (Released:2016-11-19)
参考文献数
32
被引用文献数
5

Background:Excess dietary salt is strongly correlated with cardiovascular disease, morbidity, and mortality. Conversely, potassium likely elicits favorable effects on cardiovascular disorders. In epidemiological studies, increased plasma osteoprotegerin (OPG) concentrations are associated with atherosclerosis and vascular deaths. Our study was designed to examine the effects of salt intake and potassium supplementation on plasma OPG levels in normotensive subjects.Methods and Results:The 18 normotensive subjects were selected from a rural community in China. They were sequentially maintained on low-salt diet for 7 days (3 g/day, NaCl), high-salt diet for 7 days (18 g/day), and high-salt diet with potassium supplementation for 7 days (18 g/day of NaCl+4.5 g/day of KCl). High-salt intake enhanced plasma OPG levels (252.7±13.9 vs. 293.4±16.1 pg/mL). This phenomenon was abolished through potassium supplementation (293.4±16.1 vs. 235.1±11.3 pg/mL). Further analyses revealed that the OPG concentration positively correlated with 24-h urinary sodium excretion (r=0.497, P<0.01). By contrast, OPG concentration negatively correlated with 24-h urinary potassium excretion (r=0.594, P<0.01).Conclusions:Salt loading can enhance the production of circulating OPG. Potassium supplementation can reverse the effects of excessive OPG. Our study results may improve our understanding of the roles of salt and potassium in the risk of cardiovascular disorders.
著者
Yong Zhang Ning Wu Fang Zhou Xiaoqiang Zhang Jinbao Zhang
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
IEICE Electronics Express (ISSN:13492543)
巻号頁・発行日
vol.15, no.14, pp.20180559, 2018 (Released:2018-07-25)
参考文献数
14
被引用文献数
2 4

This paper proposes a FPGA based efficient implementation of AES-GCM for wireless applications. For AES engine, we apply the DACSE algorithm to achieve a compact S-box. A new pipeline strategy is present to improve the throughput of AES engine without bring in extra resource consumption. For GHASH core, FR-KOA algorithm is present to implement a finite field multiplier (FFM). In addition, a 6-stage pipeline strategy is used to improve the FFM throughput. The proposed FR-KOA FFM can match the high-efficiency AES we designed to achieve the highly efficient AES-GCM. FPGA implementation on Xilinx FPGA, Virtex5 xc5vlx85 yielded a throughput value of 48.8 Gbps covering area of 6482 slices. The efficiency of our implementation is 7.54 Mbps/Slice which is higher than the previous works.