著者
Kariwa Hiroaki Fujii Nobuhiro Takashima Ikuo
出版者
The Graduate School of Veterinary Medicine, Hokkaido University
雑誌
Japanese Journal of Veterinary Research (ISSN:00471917)
巻号頁・発行日
vol.52, no.3, pp.105-112, 2004-11

products, a number of other chemical agents, and various physical conditions were evaluated for their ability to inactivate the severe acute respiratory syndrome coronavirus (SARS-CoV). Treatment of SARS-CoV with PVP-I products for 2 min reduced the virus infectivity from 1.17 x 10⁶ TCID₅₀/ml to below the detectable level. The efficacy of 70% ethanol was equivalent to that of PVP-I products. Fixation of SARS-CoV-infected Vero E6 cells with a fixative including formalin, glutaraldehyde, methanol, and acetone for 5 min or longer eliminated all infectivity. Heating the virus at 56℃ for 5 min dramatically reduced the infectivity of the virus from 2.6 x 10⁷ to 40 TCID₅₀/ml, whereas heating the virus for 60 min or longer eliminated all infectivity. Irration with ultraviolet light at 134μQ/cm² for 15 min reduced the infectivity from 3.8 x 10⁷ to 180 TCID₅₀/ml; however, prolonged irradiation (60 min) failed to eliminate the remaining virus, leaving 18.8 TCID₅₀/ml. We beleave that these finding will be useful for the implementation of infection control measures against SARS, and for the establishment of effective guidlines for the preventation of SARS outbreaks.

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外部データベース (DOI)

Twitter (7 users, 7 posts, 3 favorites)

Heating #covid19 virus at 56C for 5 minutes reduced its infectivity. Therefore cooked foods are safer than salads… https://t.co/zOTTpjVHz8
SARS coronavirus inactivation paper 2004: https://t.co/b9cfwwWdlS
SARSのときに、PVPや70%エタノールが不活化に有効、56℃ 5分加熱も結構いいよ、という話があったらしい。 https://t.co/HfhxeMoXB9 今回はどうかな。
@tommytommytyopp SARSの研究結果が56℃5分(1hで感染力滅)らしい? https://t.co/3Z5n37eUbF
ぱ う る ぱ 2004年の研究結果だけど歴史は繰り返しているわけだし知ってたほうがいい情報だと思われる。※μQ/cm2はキー配列からしてμw/cm2の打ち間違いかと。#coronavirus ポビドンヨード、物理的条件(加熱、紫… https://t.co/ib9kxSRQM7

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