著者
板垣 悦子/桜木 真智子/高久田 明
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
vol.41, pp.19-29, 1997-03-25

The purpose of this study was to analyze the influence of the protein powder to the effects of physical training. Female student, who had intake of the protein powder of the recommended volume, practiced physical training in the mid-level intensity. The results were as follows : 1. The skinfold thickness of the arm was reduced apparently and no change was found in the circumference of the arm. In the thorax and abdomen, both the skinfold thikness and the circumference increased. The body weight gained for period of physical training. Both the circumference and the skinfold thickness of the thigh increased. As for the lower leg, little change was found in the circumference and the skinfold thickness. 2. The influence of the protein powder to the effects of physical training was found in the body fat and in the LBM. The body fat was reduced and the LBM increased in the midst period of heavy training. After the protein powder was ceased to have as nutrition during the training period, no change was found in the LBM. 3. The systolic blood pressure after running decreased and the diastolic blood pressure increased under the condition of the present study. The heart rate also varied under the condition. The heart rate decreased before and after running. The recovery time of heart rate was found to be shorter than that before the present experiment.
著者
板垣悦子
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
vol.45, pp.1-11, 2001
被引用文献数
1

A stimulation to receive from the five senses becomes a terrible key when we pursue agreeableness of life environment for us. The stimulation that it receives from the five senses is for mental unrest by a personal image to give influence to a body. In this study, we used six colors (red, blue, green, yellow, white, black) as stimulation to receive from sight. As the next experiment, we played music in a color room and examined influence to blood pressure value and heart rate. The purposes of our study are to examine "color environment" and "sound environment" to make better you life environment. The consequences are as follows. In stimulation only of color, "red" let systric blood pressure increase, and "blue" did decrease it. There were many things which such as "blood", "fight", "a sense of being oppressed" become exalted as for the image of "red" that blood pressure value let increase. As for "the blue" that blood pressure value decreased, "the deep sea" "calms", and there were many things which had a feeling of relaxation of "sleepiness". The images of "blue", "red" and "yellow" when they're added musics were so different compared with only the color. "The red" that increased only from the color decreased, and, as for "the blue", dispersion was found in a value. Yellow showed same condusion. In case of the stimulation only from color, the increase and decrease of systric blood pressure during staying the room and after leaving were same tendencies. But we moderated influence of color when we added music. A person of stimulation of music received influence in systric blood pressure than stimulation only of color more, and the person who did not hear music usually was inexpensive. Width of change of heart rate was bigger when we added to music. And the values when he was in the room and he left there were perfectly opposite, and they never settled down. There were various kinds of the images that each people received from the five senses. And blood pressure value and reaction of heart rate count depended on each people. These things mean that it is dangerous to use color environment and sound environment uniformly at the public place. It is not good to watch only from one side to have "better and healthy environment for body" ready. And we must not ignore a characteristic of one person unique in the situation either. In brief, it was thought that a study from wide fields such as psychology, physiology, medicine, human engineering was necessary.
著者
福井 美園 滝谷 玲子 多田 敬三
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
no.25, pp.p49-59, 1981-03

The decomposition of 1-nitroso-1-butyl-3,3-dimethylurea (DM-NBU), which was found to have both leukomogenic and vaginatumorigenic activities on female rats, was studied in the buffer solutions of various pH values from 2 to 12 at 37℃. It was found that the decomposition velocity of DM-NBU was lowest in the neutral medium and increased as pH values either increased or decreased from 7,and the velocity was generally much lower than that of 1-nitroso-1-butylurea (NBU). The effect of the concentration of DM-NBU on the velocity has not yet been examined in detail, but it has been found that lower concentrations resulted in more rapid decomposition than higher ones did in the range of pH examined only except at pH 10. The main decomposition products of DM-NBU were carbondioxide, dimethylamine, 1-butanol and 2-butanol. Although the above two isomers of butanol were also detected and determined in the case of NBU and their total amounts were almost equal at each pH values of 2,7 and 12,in the case of DM-NBU, they were almost equal in the range of pH values from 12 to 6 but they fell suddenly at pH 5 and, thereafter, gradually decreased as pH values decreased. The ratio of the amount of 1-butanol to that of 2-butanol was 1.8-2 in the range of pH tested. The determination of the residual amounts of DM-NBU was made absorption-spectrophotometrically and that of the butanols was carried out gaschromatographically after the decomposition proceeded completely.
著者
鈴木 厚子 福井 美園 中安 寿美子 滝谷 玲子 多田 敬三
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
vol.28, pp.1-15, 1984-03-25

The reaction of N-nitroso-N-butylurea (NBU) with an equivalent of L-α-aminoacid was made in the buffer solution of pH 7.2 at 37℃ for 3 weeks. α-Carbamoyl-aminoacid was isolated and identified for each α-aminoacid examined together with the decomposition-products of NBU such as 1-and 2-butanols, urea and a slight amount of butylurea. A quantitative research was also carried out for L-methionine and L-leucine by high performance liquidchromatography. It was found that about 60% of L-methionine and 53% of L-leucine was carbamoylated respectively with an equivalent of NBU during 5 days, but, thereafter, no appreciable further carbamoylation was observed, and also that 83% of methionine reacted with twice equivalent of NBU. The velocity and products of decomposition of NBU in the buffer solutions of various pH were reinvestigated. The minimum rate constant for the apparent first-order decomposition was found in the region of pH3. The determination of butanols produced by gaschromatography of ether extracts from the reaction mixture showed that not only their total amounts were practically unvaried but also the ratio of 1-butanol to 2-butanol was almost equal value of 2.0 in various pH regions. The amount of urea or butylurea produced in each pH solution was relatively estimated by semiquantitative thin-layer chromatography. In the case of urea, no appreciable difference was observed except in the regions of pH3 and pH4,where urea was found to be a minor product and, instead, an unknown product was detected, whereas the formation of butylurea was slight in higher pH regions than pH5,however, in more acidic medium denitrosation seemed to be considerable although it might be a side reaction in the whole decomposition-pathway. Some considerations and discussions were made on the mechanism of decomposition of NBU, and also on the results from the quantitative study for the reaction of NBU with α-aminoacids.
著者
友田 正司/加藤 祥子
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
vol.11, pp.6-9, 1966-05-20

The water-soluble substances of the tuberous roots of Ophiopogon japonicus Ker-Gawler var. genuinus Maximowicz were obtained in 92% yield of the dry crude drug. The water-extract was fractionated by the chromatography on a column of charcoal-Celite, and D-glucose, D-fructose, sucrose and the other five oligosaccharide fractions were obtained. The carbohydrates have been examined by the use of paper partition chromatography and gas-liquid chromatography. D-Glucose, D-fructose and sucrose were identified respectively as D-glucose benzylphenylhydrazone, D-fructose methylphenylosazone, and sucrose octaacetate. The obtained all oligosaccharides were non-reducing glucofructan. The results of quantitative determinations of the monosaccharides and oligosaccharides showed that the water-extract contains 9.1% of D-glucose, 6.7% of D-fructose, 4.8% of sucrose and 56.7% of the other oligosaccharides.
著者
友田 正司/加藤 祥子
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
vol.13, pp.35-39, 1968-10-20

The main oligosaccharide fraction obtained from the water extract of the tuberous roots of Ophiopogon japonicus K_<ER>-G_<AWLER> var. genuinus M_<AXIMOWICZ> was purified by the gel filtration on Sephadex G-25,and separated into three oligosaccharides. They were a heptasaccharide composed of one glucose unit and six fructose units, a hexasaccharide composed of one glucose unit and five fructose units, and a pentasaccharide composed of one glucose unit and four fructose units. Methylation and periodate oxidation studies showed that the each oilgosaccharide possesses the structure consisted of a chain of 2→1 linked D-fructofuranose units having a D-glucopyranose residue, joined by a type of sucrose bond, on the end.
著者
小田原 宏行
出版者
慶應義塾大学
雑誌
共立薬科大学研究年報 (ISSN:04529731)
巻号頁・発行日
vol.42, pp.11-20, 1998-06-25

D_n symmetry is represented by the rotations about the center of the D_n and an axis of symmetry. In this paper, I introduce symmetrical mapping using four parameters on the plane with D_n symmetry. Under this mapping, I show how the chaos is created, and the characteristic features of chaos are shown for several values of n. We can see that the symmetry breaking in the symmetrical mapping is possible associated with less symmetrical figures in the case n=8.