- 一般社団法人 日本生物物理学会
- 生物物理 (ISSN:05824052)
- vol.50, no.1, pp.018-022, 2010 (Released:2010-01-25)
One of the major goals in evolutionary developmental biology is to elucidate the relationship between gene regulatory networks and the diverse morphologies. Segmentation in arthropod embryogenesis represents a well-known example of body plan diversity. Striped patterns of gene expression that lead to the future body segments appear simultaneously or sequentially, respectively. To reveal the basic differences in the network structure, we have numerically evolved hundreds of gene regulatory networks. By analyzing the topologies of the generated networks, we show that the characteristics of striped pattern are determined by Feed-Forward Loops (FFLs) and negative Feed-Back Loops (nFBLs).