- Hirosaki University Graduate School of Medicine,Hirosaki Medical Society
- 弘前医学 (ISSN:04391721)
- vol.71, no.2-4, pp.138-145, 2021 (Released:2021-03-15)
Objective: The incidence of dementia is increasing in developed countries, and early detection and treatment are
important. Considering that olfactory disorders are correlated with cognitive dysfunction, olfactory testing might
be a useful screening tool for dementia. In the present study, we investigated whether a simple olfactory test could
predict the short-term progression of cognitive decline using data from a longitudinal study of a community-dwelling
Subjects and Methods: Subjects were participants of the Iwaki Health Promotion Project, a community-based program
aimed at improving average life expectancy. The subjects were examined using a 4-item modified Pocket Smell Test
(mPST) and the Mini-Mental State Examination( MMSE) in 2016 and 2017. The relationship between the change in
MMSE scores and olfactory identification ability in 2016 was analyzed in subjects with good MMSE scores in 2016.
Results: Among participants in their 60s and 70s, the olfactory-impaired group showed significantly lower MMSE
scores in 2017 than those of the good-olfaction group.
Conclusion: Olfactory testing may be a tool for early detection of the onset of cognitive decline in elderly people.