著者
林 伸和
出版者
日本香粧品学会
雑誌
日本香粧品学会誌 (ISSN:18802532)
巻号頁・発行日
vol.40, no.1, pp.12-19, 2016-03-31 (Released:2017-05-12)
参考文献数
55

Acne is a chronic skin condition that affects patient quality-of-life. More than 90% of the Japanese population experiences acne at some point in their lifetime. Comedones, which are caused by excess sebum secretion and hyperkeratosis in the infundibulum, appear in the first stage of acne. The second stage involves inflammatory eruptions mainly caused by Propionibacterium acnes. Benzyl-peroxide (BPO), and fixed combination products of BPO and clindamycin, became available in Japan in 2015. BPO acts on both comedones and inflammatory eruptions, and it can be used for maintenance therapy because it does not induce antibiotic-resistant P. acnes. To achieve early results and to prevent the emergence of antibiotic-resistant bacteria, the revised guidelines for the treatments of acne in Japan recommend combination therapy with adapalene, antibiotics, and BPO, including fixed-combination topical agents, in the acute inflammatory phase. Once inflammation has improved, comedones treatment should be continued with adapalene and/or BPO in the maintenance phase to achieve further improvement and to prevent recurrence. The acute phase lasts approximately 3 months, and antibiotics should not be used for maintenance therapy. Sometimes, inflammatory eruptions can result in hypertrophic and atrophic scars that cannot be treated completely. Early aggressive treatment is important to prevent scars. Skin care and cosmetics are also important in the treatment of acne as well as to avoid aggravation. The guidelines recommend twice-daily face washing with a suitable cleanser. Non-comedogenic moisturizers should be used by patients who have dry skin and by those who need to avoid the adverse effects of adapalene and BPO. There is no reliable evidence connecting certain foods and acne, and we should not uniformly restrict specific foods. There is compelling evidence demonstrating the efficacy of azelaic acid and chemical peels with glycolic acids in the treatment of acne. Camouflage also helps acne patients improve their quality of life. To improve acne treatments, more evidence is needed regarding the integration of treatments and skin care.

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【ニキビを減らすために】 ニキビに関するスキンケアや食事法が色々出回ってますが、どれも医学的な根拠は十分とは言えないようです。 でも色々な研究を基に現時点では、 『アダパレン』、『過酸化ベンゾイル』が「炎症抑制」「再発防止」に関して最有力だそうです。https://t.co/TRxmMulWVn https://t.co/gwCqUyH5aa
@kawaiiganmen 参考文献です https://t.co/gRbHsUAI1n 糖質は関係がかなりみられるようで、低糖質、低GLの食品を中心にするのも良さそうです
ニキビについての論文を読んでみる https://t.co/Vq807xTdC4 https://t.co/XzFyPAt9jj
一方で、低GI値食品を中心とした食事はそのような食事をしない集団よりもニキビの発生が抑えられる。ただ炭水化物ダイエットとは異なるので注意が必要。 参考文献:https://t.co/eTuEFocevB #ニキビ
チョコ、糖質、ミルクなどの食品がニキビの発生源となる明確なエビデンスはない。無関係ではないが、制限したからといって発生が抑えられることはなく、我慢することによるストレスを考えるとむやみに制限する必要はない。 参考文献:https://t.co/eTuEFocevB #ニキビ

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