1 0 0 0 OA 口腔癌治療時に汎用される院内製剤アズノール含嗽水の安定性と細菌学的検討
- 著者
- 牛山 美奈 池田 龍二 新田 哲也 田實 裕介 宮脇 昭彦 山口 辰哉 下堂薗 権洋 牛之濱 風見 松井 竜太郎 杉原 一正 中村 典史 山田 勝士
- 出版者
- JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY
- 雑誌
- 歯科薬物療法 (ISSN:02881012)
- 巻号頁・発行日
- vol.27, no.3, pp.143-150, 2008-12-01 (Released:2010-06-08)
- 参考文献数
- 14
In our hospital, hospital preparations of Azunol Saline Gargle (AS, saline solution containing 0.006% sodium gualenate hydrate), and Azunol Lidocaine Saline Gargle (ALS, AS with lidocaine) are used as a treatment for oral cancer with oral mucositis. However, little is known about the stability and microbiological safety of AS and ALS. In this study, the stability and microbiological safety of AS and ALS were assessed as the pH and the percent of sodium gualenate hydrate remaining in both preparations after exposure to various light and temperature conditions and the colony formation, respectively. As a result, we found that under fluorescent lamp lighting, AS and ALS were stable for 7 days at 4°C compared with 25t or room temperature. Furthermore, by light shielding, they were stable for at least 14 days at 4°C. Bacterial contamination of AS was prevented by preserving at 4°C for 14 days.We have demonstrated the stability and microbiological safety of AS and ALS and established an appropriate preservation method. This study provides useful information regarding the management of oral mucositis in oral cancer patients.
- 著者
- 牛山 美奈 池田 龍二 新田 哲也 田實 裕介 宮脇 昭彦 山口 辰哉 下堂薗 権洋 牛之濱 風見 松井 竜太郎 杉原 一正 中村 典史 山田 勝士
- 出版者
- JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY
- 雑誌
- 歯科薬物療法 (ISSN:02881012)
- 巻号頁・発行日
- vol.27, no.3, pp.143-150, 2008
In our hospital, hospital preparations of Azunol Saline Gargle (AS, saline solution containing 0.006% sodium gualenate hydrate), and Azunol Lidocaine Saline Gargle (ALS, AS with lidocaine) are used as a treatment for oral cancer with oral mucositis. However, little is known about the stability and microbiological safety of AS and ALS. In this study, the stability and microbiological safety of AS and ALS were assessed as the pH and the percent of sodium gualenate hydrate remaining in both preparations after exposure to various light and temperature conditions and the colony formation, respectively. As a result, we found that under fluorescent lamp lighting, AS and ALS were stable for 7 days at 4°C compared with 25t or room temperature. Furthermore, by light shielding, they were stable for at least 14 days at 4°C. Bacterial contamination of AS was prevented by preserving at 4°C for 14 days.<BR>We have demonstrated the stability and microbiological safety of AS and ALS and established an appropriate preservation method. This study provides useful information regarding the management of oral mucositis in oral cancer patients.
1 0 0 0 OA 口唇口蓋裂における早期母子相互作用の臨床的検討
本研究の目的は,口唇口蓋裂(Cleft Lip and/or Palate: CLP)の子どもとその家族に対する有効な心理的援助を実現するための方法論を提示することである。そのため(1)CLP児の母子関係に潜在する心理的問題,(2)CLPによる障碍が子どもの対他者関係,特に家族に及ぼす影響,(3)成人CLP者の回想における母子関係の変容過程を検討した。結果は,(1) 関係性構築の阻害要因と促進要因,(2) 構音障害への対処の重要性,(3) CLP者の人生岐路におけるレジリエンス(回復力)という観点から考察された。