3 0 0 0 OA 400ml採血後の造血過程に関する血液学的検討
- 著者
- 吉田 雅司 杉原 一正 水枝谷 渉 山下 佐英
- 出版者
- 特定非営利活動法人 日本口腔科学会
- 雑誌
- 日本口腔科学会雑誌 (ISSN:00290297)
- 巻号頁・発行日
- vol.41, no.4, pp.721-725, 1992-10-10 (Released:2011-09-07)
- 参考文献数
- 12
The recovering process of the anemia following 400ml blood donation in healthy female volunteers was studied hematologically. The advanced erythropoietic ability was observed from the first day following the phlebotomy. On the 14th day, the rates of reticulocyte and the mean corpuscular hemoglobin concentration normalized and the serum erythropoietin level indicated a maximum in spite of the decreases of serum iron and ferritin.There were no obvious side effects following a 400ml phlebotomy for healthy females. It was suggested that the 2 weeks after the 400m1 autologous blood donation would be a suitable period for orthognathic surgery.
2 0 0 0 OA アンギオテンシンII受容体拮抗薬が誘因と推察された舌・口底部の血管性浮腫の1例
- 著者
- 坂元 亮一 上川 善昭 永山 知宏 杉原 一正
- 出版者
- 日本歯科薬物療法学会
- 雑誌
- 歯科薬物療法 (ISSN:02881012)
- 巻号頁・発行日
- vol.29, no.1, pp.21-24, 2010-04-01 (Released:2010-08-20)
- 参考文献数
- 18
We report a case of angioedema in the tongue and oral floor potentially induced by angiotensin II receptor blockers (ARB).A 77-year-old woman with a history of hypertension was treated with an ARB, and edematous lesions in the tongue and oral floor suddenly occurred about one week after the start of the treatment. She visited an emergency hospital, and was prescribed serrapeptase, a complex of betamethasone and chlorpheniramine maleate, and epinastine hydrochloride. But since the edema was poorly controlled, she was referred to our department. The ARB was strongly suspected to have caused the angioedema, so we stopped the ARB that she was taking. Edema disappeared one day after the onset of symptoms, and there has been no recurrence of symptoms after the termination of ARB treatment.
1 0 0 0 OA 口腔癌治療時に汎用される院内製剤アズノール含嗽水の安定性と細菌学的検討
- 著者
- 牛山 美奈 池田 龍二 新田 哲也 田實 裕介 宮脇 昭彦 山口 辰哉 下堂薗 権洋 牛之濱 風見 松井 竜太郎 杉原 一正 中村 典史 山田 勝士
- 出版者
- JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY
- 雑誌
- 歯科薬物療法 (ISSN:02881012)
- 巻号頁・発行日
- vol.27, no.3, pp.143-150, 2008-12-01 (Released:2010-06-08)
- 参考文献数
- 14
In our hospital, hospital preparations of Azunol Saline Gargle (AS, saline solution containing 0.006% sodium gualenate hydrate), and Azunol Lidocaine Saline Gargle (ALS, AS with lidocaine) are used as a treatment for oral cancer with oral mucositis. However, little is known about the stability and microbiological safety of AS and ALS. In this study, the stability and microbiological safety of AS and ALS were assessed as the pH and the percent of sodium gualenate hydrate remaining in both preparations after exposure to various light and temperature conditions and the colony formation, respectively. As a result, we found that under fluorescent lamp lighting, AS and ALS were stable for 7 days at 4°C compared with 25t or room temperature. Furthermore, by light shielding, they were stable for at least 14 days at 4°C. Bacterial contamination of AS was prevented by preserving at 4°C for 14 days.We have demonstrated the stability and microbiological safety of AS and ALS and established an appropriate preservation method. This study provides useful information regarding the management of oral mucositis in oral cancer patients.
- 著者
- 牛山 美奈 池田 龍二 新田 哲也 田實 裕介 宮脇 昭彦 山口 辰哉 下堂薗 権洋 牛之濱 風見 松井 竜太郎 杉原 一正 中村 典史 山田 勝士
- 出版者
- JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY
- 雑誌
- 歯科薬物療法 (ISSN:02881012)
- 巻号頁・発行日
- vol.27, no.3, pp.143-150, 2008
In our hospital, hospital preparations of Azunol Saline Gargle (AS, saline solution containing 0.006% sodium gualenate hydrate), and Azunol Lidocaine Saline Gargle (ALS, AS with lidocaine) are used as a treatment for oral cancer with oral mucositis. However, little is known about the stability and microbiological safety of AS and ALS. In this study, the stability and microbiological safety of AS and ALS were assessed as the pH and the percent of sodium gualenate hydrate remaining in both preparations after exposure to various light and temperature conditions and the colony formation, respectively. As a result, we found that under fluorescent lamp lighting, AS and ALS were stable for 7 days at 4°C compared with 25t or room temperature. Furthermore, by light shielding, they were stable for at least 14 days at 4°C. Bacterial contamination of AS was prevented by preserving at 4°C for 14 days.<BR>We have demonstrated the stability and microbiological safety of AS and ALS and established an appropriate preservation method. This study provides useful information regarding the management of oral mucositis in oral cancer patients.
1 0 0 0 本邦におけるエナメル上皮腫の病態と治療法に関する疫学的研究
- 著者
- 柴原 孝彦 森田 章介 杉原 一正 箕輪 和行 山口 朗 山田 隆文 野村 武史
- 出版者
- Japanese Society of Oral Oncology
- 雑誌
- 日本口腔腫瘍学会誌 (ISSN:09155988)
- 巻号頁・発行日
- vol.21, no.3, pp.171-181, 2009-09-15
- 被引用文献数
- 7 6
1995年1月から2004年12月の10年間に本学会評議員が所属する61施設で,エナメル上皮腫と診断,治療された947症例に対してアンケートによる疫学的調査を実施した。性別は男性581例,女性366例であり,年代別にみると男性は20歳代で18.6%とピークを示し,女性では10歳代で23.2%とピークを示した。また部位では臼歯部が最も多く55.6%であった。臨床症状では疼痛が46.6%と最も多く,次いで腫脹が13.6%であった。エックス線所見は単房性が50.7%,多房性が40.4%であった。2005年のWHO歯原性腫瘍組織分類ではsolid/multicystic typeが74.5%と最も多く,次いでunicystic typeが17.0%,desmoplastic typeが4.1%,extraosseous/peripheral typeが3.0%であった。治療法では,顎骨保存療法(開窓145例15.9%,摘出開放創187例20.5%,摘出・掻爬289例31.8%を含む)が74.0%,顎骨切除療法が24.1%であった。