著者

古田 睦広 尾崎 元昭 原田 禹雄 高橋 俊一郎 村上 元正 松本 繁雄

出版者

一般社団法人 国立医療学会

雑誌

医療 (ISSN:00211699)

巻号頁・発行日

vol.26, no.2, pp.139-144, 1972 (Released:2011-10-19)

参考文献数

14

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Histopathological examination of tuberculosis was done on 107 autopsy cases in Komyoen Leprosarium from 1962 to 1970. Seventeen cases showed pulmonary tuberculosis, including healed and calcified lesions. The average age of these cases was 66.6. Active pulmonary tuberculosis was found in 10 cases; half of them formed tuberculous cavity. Only 2 cases showed remarkable extension of the disease to the other organs. This was quite different from the formm of tuberculosis before 1900 which was predominantly accompanied with direct or miliary type extension. Gaseous pneumonia of 4 cases between 1967 and 1666 suggested possibility of reinfection on the aged. Active tuberculosis on the aged seemed to have a tendency to become caseous pneumonia. There was no correlation between the types of leprosy and tuberculosis. We deny any specific relation of tuberculosis to leprosy patients.

著者

田中 敏 金森 修弘 古田 睦広

出版者

日本先天異常学会

雑誌

先天異常 : 日本先天異常学会会報 : official journal of Congeital Anomalies Research Association of Japan (ISSN:00372285)

巻号頁・発行日

vol.6, no.3, pp.198-199, 1966-09-30

著者

古田 睦広 鳥居 昭三 上野 一也

出版者

日本先天異常学会

雑誌

先天異常 : 日本先天異常学会会報 : official journal of Congeital Anomalies Research Association of Japan (ISSN:00372285)

巻号頁・発行日

vol.5, no.4, 1965-12-28

著者

中山 志郎 堺 幹太 疋田 善平 服部 譲 三宅 儀 古田 睦広 井谷 舜郎 星野 孝

出版者

一般社団法人 日本血液学会

雑誌

臨床血液 (ISSN:04851439)

巻号頁・発行日

vol.11, no.6, pp.687-696, 1970 (Released:2008-10-31)

参考文献数

32

被引用文献数

7

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This report deals with our recent observations on 3 cases of atypical acute leukemia difficult to differentiate from aplastic anemia. They were all males, over 60 years old and had lack of definite signs of acute leukemia in their clinical pictures. Onset was insidious, clinical course was mild and prolonged, and physical examinations were unremarkable except for pallor.Examinations of the blood showed marked pancytopenia with few or no immature cells. Aspirated bone marrow specimens were markedly hypocellular with an infiltration of a small number of blast cells which were characterized by bizzare shape, negative peroxidase reaction and prominent nucleoli and were barely identifiable as myeloblast by the phase contrast microscopical findings.Chromosomal analysis of cultured peripheral leukocytes disclosed many aneuploid cells including few of 21-Trisomy in 2 cases.Anemia remained refractory to various therapies, but blood transfusions and administration of prednisolone made the patients' general condition improved.One case died of unknown cause suddenly after blood transfusion. The principal anatomical findings of this case were bone marrow hypoplasia and mild infiltrations of immature cells in the bone marrow, lymphnodes, spleen and liver.It is widely known that the clinical picture and course of malignant tumors in aged persons are somewhat different from those in younger people. On this aspect, characteristics of acute leukemia in advanced age group are discussed mainly in association with changes in the immunobiologic capabilities and in the functions of endocrine organs.