著者

清水 孜 広鰭 律子 野村 泰子 栗飯原 景昭 宮木 高明

出版者

National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee

雑誌

Japanese Journal of Medical Science and Biology (ISSN:00215112)

巻号頁・発行日

vol.24, no.5, pp.271-279, 1971 (Released:2010-03-19)

参考文献数

13

被引用文献数

1 3

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In order to prove sodium toxicity of MSG, baby chicks known to be the most susceptible one to sodium chloride were chosen as the experimental animal. Almost isotonic solution of MSG, NaCl or monopotassium glutamate was given ad libitum as the sole source of drinking water. Two-day old chickens given MSG died of gout within a few days and showed higher mortality and lesions severer than those given physiological saline, while none died nor was weakened among those receiving monopotassium glutamate. Very rapid development of kidney lesions and a large amount of urate deposits were the two main features resulting from MSG ingestion, and primary histological changes were tubular degeneration and tophi obstruction in collecting ducts. Even at half concentration, MSG ingestion caused lobar atrophy in the kidney and some died of gout. Besides sodium toxicity, glutamate counterpart is suspected of contributing to uric acid synthesis.

著者

堀江 義一 山崎 幹夫 宮木 高明 宇田川 俊一

出版者

公益社団法人 日本食品衛生学会

雑誌

食品衛生学雑誌 (ISSN:00156426)

巻号頁・発行日

vol.12, no.6, pp.516-519, 1971-12-05 (Released:2010-03-01)

参考文献数

11

被引用文献数

1

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Fungal content of 24 samples of various types of spices of which a half was domestic and the others were collected from the markets in U.S.A., was surveyed from the hygienic point of view on foodstuffs. From 15 mold-positive samples, 12 were estimated under heavy contamination. Twenty eight fungi were isolated from these spices and were identified. Except a few Fungi Imperfecti and Mucorales, the majority of the species was found to be belonging to the genera Aspergillus and Penicillium. In the genus Aspergillus, the members of A. glaucus, A. flavus, A. niger, A. terreus and A. versicolor groups were the predominant species on the Japanese samples. In Penicillium, the series commonly found was P. chrysogenum only appearing in paprika of Japanese sample. The important contaminants in U.S.A. samples were identified as representatives of the A. glaucus group. No aflatoxins were detected in CHCl3 extracts of the rice culture of A. flavus which were found in Japanese sage and pepper. Since some spices such as garlic powder are known to have a bacteriostatic or bacteriocidal property, it may be suggested from the result obtained that some spices are not subject to spoilage.