3 0 0 0 IR 南アルプス山中ライフル銃狩猟誤射事件
著作者の意向により本文は非公開です。冊子版をご覧ください。 昭和61年2月13日、狩猟会のリーダーである50歳の男が山梨県の南アルプス山中でイノシシ狩中ライフル銃が暴発して死亡したとの届け出が警察になされた。法医解剖により、被害者には背面腰部に遠射による射入銃創が、陰茎根部直上に射出銃創が認められた。めずらしいことに陰茎包皮内に再貫通銃創もみられた。死因は腸および腸間膜破裂ならびに腰仙椎の粉砕骨折による腹腔内出血と考えられた。凶器は口径約8mm前後の小銃であると推定された。警察での取調べの結果、加害者は狩猟会の仲間の1人である43歳の男であることがわかった。彼は被害者をイノシシとまちがえ約70mほどの遠距離から口径7.8mmのライフル銃で射ってしまったと告白した。後の現場の見分によっても、被害者はおそらくしゃがんでいる姿勢で、背面を射たれたことが確かめられた。 On 13 February 1986, there was a report to the police that a 50-year-old man, leader of a hunting party ,accidentally shot himself to death with his rifle while hunting wild boars in the South Alps of Yamanashi Prefeture. Medicolegal examination revealed that the deceased sustained a distance entrance gunshot wound in the lumbar region of the back and an exit wound just above the root of the penis. A remarkable re-penetrating gunshot wound through the prepuce of the penis was seen, too. The cause of death was considered to be an intra-abdominal haemorrhage due to ruptures of bowels and the mesenterium as well as crush fractures of the lumbo-sacral vertebrae. The wearpon was determined to be a firearm of about 8 mm calibre. Crime investigation by the police disclosed that the assailant was a 43-year-old man, a member of the hunting party. He confessed that he misstook the victim for a wild boar and shot the victim with his rifle of 7.8 mm calibre at a range of about 70 m. Subsequent investigation of the scene confirmed that the victim had been shot in the back probably in a squatting posture.
2 0 0 0 OA Bromazepamの代謝に関する研究(第1報)尿中代謝産物の単離と同定
- 著者
- 沢田 英夫 矢野 博子 木戸 啓
- 出版者
- 公益社団法人日本薬学会
- 雑誌
- 藥學雜誌 (ISSN:00316903)
- 巻号頁・発行日
- vol.92, no.10, pp.1237-1241, 1972-10-25
Besides the unchanged drug, two major metabolites were found from the urine of animals that received orally high doses of bromazepam, 7-bromo-1,3-dihydro-5-(2-pyridyl)-2H-1,4-benzodiazepin-2-one. The metabolites were purified by column chromatography on silica gel and recrystallization. From the spectral and elemental analysis data, the structure of these metabolites were identified as 2-amino-5-bromobenzoylpyridine and assumed to be 2-amino-5-bromo-3-hydroxybenzoylpyridine, the latter being excreted as its glucuronide in the urine. It may be concluded that bromazepam after opening of the diazepine ring undergoes a process of hydroxylation.