著者

山下 栄次 松野 隆男

出版者

公益社団法人 日本水産学会

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.58, no.12, pp.2277-2282, 1992 (Released:2008-02-29)

参考文献数

25

被引用文献数

3 4

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A series of new apocarotenoids, micropteroxanthins, has been isolated from the integuments of the black bass Micropterus salmoides, namely α-micropteroxanthin A, α-micropteroxanthin B, β-micropteroxanthin, and 7, 8-didehydro-β-micropteroxanthin. These structures have been de-termined to be (3S, 6S)-11', 12'-dihydro-10'-apo-ε-carotene-3, 10'-diol, (3R, 6S)-11', 12'-dihydro-10'-apo-ε-carotene-3, 10'-diol, (3R)-11', 12'-dihydro-10'-apo-β-carotene-3, 10'-diol, and 3(R)-7, 8-didehydro-11', 12'-dihydro-10'-apo-β-carotene-3, 10'-diol, respectively. The possible metabolic pathways of carotenoids to new apocarotenoids, micropteroxanthins, by an eccentric cleavage in the black bass have been proposed.

著者

津島 己幸 真岡 孝至 勝山 政明 小塚 睦夫 松野 隆男 徳田 春邦 西野 輔翼 岩島 昭夫

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.18, no.2, pp.227-233, 1995-02-15 (Released:2008-04-10)

参考文献数

26

被引用文献数

43 77

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As a screening study for anti-tumor promoters, 51 carotenoids with diverse structures were examined for their inhibitory effects on the Epstein-Barr virus activation activity of 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. The results showed that most of the carotenoids exhibited inhibitory activity, and in general, no cytotoxicity on Raji cells was observed in the assay. Among the carotenoids, β-cryptoxanthin, lutein, and lactucaxanthin showed the strongest inhibitory activity, superior to the well known anti-tumor promoter, β-carotene. Heteroxanthin, peridinin, and halocynthiaxanthin showed cytotoxicity at the high concentration (1000 molar ratio per TPA), but indicated a strong inhibitory effect at the lower concentrations, which were only weakly toxic (500 and 100 molar ratios). Based on these results, the essential moiety for the activity of carotenoids was considered to be the 3-hydroxy-ε-end group.

著者

松野 隆男 永田 誠一 佐藤 嘉純 渡辺 哲夫

出版者

日本水産學會

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.40, no.6, pp.579-584, 1974

被引用文献数

5

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The carotenoid pigments from the fin and skin of horse mackerel, swellfishes, porcupinefishes and striped mullet were investigated. Tunaxanthin was predominant in horse mackerel (63-69%), swellfishes (33%) and porcupinefishes (56%). The following carotenoids were identified and their contents determined in the respective fishes: β-carotene(-, -, 4%), α-cryptoxanthin (2-trace, 3, 10%), cryptoxanthin (-, 10%, -), lutein(15-19, 3, 6%), zea1xanthin(10-16, 33, 16%), diatoxanthin(-, 7%, -), cynthiaxanthin(-, 8%, -), α-doradecin (-, 3, 1%) and astacene (-, trace, 1%), respectively.<br>Carangoxanthin originally reported in horse mackerel by Hirao was not detected in fishes collected at various seasons and places in spite of our detailed investigation.<br>In contrast with the above fishes, striped mullet contained zeaxanthin (68%) and lutein (20%) as the major carotenoids and a relatively small amount of tunaxanthin (6%).