著者
林 茂保
出版者
北海道東海大学
雑誌
北海道東海大学紀要. 芸術工学部 (ISSN:02884992)
巻号頁・発行日
vol.7, pp.9a-13a, 1987-03-30

Finland is the only country of the European Democratic Countries which has concluded The Treaty of Mutual Aid with Soviet Union. Finland has been acknowleding her own foreign bolicy as 'pro-Soviet and Neutralistic', but her peculiar circumstances to the Soviet Union has been called 'Finlandization' in the branch of Political Science. Since Prime Minister Nakasone addressed the audience in his way side speech on the day of the announcement of the election of the House of Councilors as if it (Japan) did nothing to prepare for defending our own country, it (Japan) would become such a country as Finland, which seems like a pseudo-satellite state of the Soviet Union, and aroused criticism, 'Finlandzation' has been an object of discussion in our country. There are now different definitions of 'Finlandization', i.e. N. Elviek says 'It is the condition that a certain country is gradually being controlled by the affairs of the state from her diplomacy to her domestic administration due to having repeated its concessions to tee Soviet Union diplomatically by tha country and Osamu Eya says, 'It is the way how a lesser power, neighboring a superpowers (like U.S.A. and the Soviet Union) maintains her neutrality, keeps her independence by its clever diplomacy, without losing her sovereignty and so on. I'd like to demonstrate which definition is the nearest one to the truth of 'Finlandization.
著者
芝山 雄老 松本 和基 大井 玄 中田 勝次 筧 紘一 清水 修 茂在 敏司 榊原 茂樹 佐藤 久夫 小林 茂保
出版者
The Japan Society of Hepatology
雑誌
肝臓 (ISSN:04514203)
巻号頁・発行日
vol.24, no.2, pp.208-216, 1983

ヒトβ型インターフェロン(HuIFN-β)投与肝細胞癌の一症例を経験した.症例は62歳男,会社役員.入院時すでに肝右葉全域および左葉の一部に肝細胞癌が認められ,手術不可能と判断し,HuIFN-βの大量投与(筋注総量4,671×10<SUP>4</SUP>IU,静注総量2,866×10<SUP>4</SUP>IU,肝動脈内注入250×10<SUP>4</SUP>IU)が行われた.肝動脈内注入直後一過性にα-Fetoprotein値の低下が認められたが,筋注および静注では著効を示さず,癌は徐々に増大した.病理解剖学的には多核巨細胞化した癌細胞および原形質が泡沫化した癌細胞の出現および癌細胞の壊死に陥る傾向の乏しいことが注目された.これらの所見はHuIFN-β非投与肝細胞癌例にも多少認められるので,HuIFN-β投与による特異的変化であるとは言えないが,それらの程度が著しく高度であったことよりHuIFN-β投与と何らかの関係が存在するのではないかと考えられた.本症例では臨床的にも病理解剖学的にも肝細胞癌に対するHuIFN-βの著しい治療効果は認められなかった.